Bilateral vascular supply in juvenile nasopharyngeal angiofibromas

Arthur W. Wu, Sarah E. Mowry, Fernando Vinuela, Elliot Abemayor, Marilene B. Wang

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

Objectives: Juvenile nasopharyngeal angiofibroma (JNA) is a rare, benign tumor of the nasopharynx, exclusively affecting males in their teens and twenties. Historically, it has been thought that JNAs primarily receive their blood supply from the ipsilateral external carotid system. We demonstrate in our case series and literature review that bilateral vascular supply in these tumors is, in fact, very common. Study Design: Case series and literature review. Methods: We present four consecutive cases of JNA in a three-year period from a major tertiary care center. A literature review on the topic of vascular supply in JNA was performed. Results: The first patient's preoperative angiogram demonstrated only right-sided blood supply. However, significant bleeding was encountered, and an intraoperative angiogram showed significant new vascularization from the left ascending pharyngeal artery (APA), which was embolized. The surgery was completed successfully without further significant hemorrhage after converting to an open approach. Preoperative angiograms from the next three patients demonstrated bilateral vascular supply. Embolization and endoscopic resection was successful in these cases. Review of the literature demonstrates that bilateral vascular supply is not commonly documented; however, it may be more frequent than previously thought. Other series demonstrate bilateral vascularity from 0% to 100%. Combining patients from nine studies, including our own, we found that 57 of 157 (36%) patients had tumors with bilateral vascular supply. Conclusions: Bilateral vascular supply may be an underappreciated factor in JNA, and thorough radiographic investigation via angiography of bilateral carotid systems should be routinely done preoperatively.

Original languageEnglish (US)
Pages (from-to)639-643
Number of pages5
JournalLaryngoscope
Volume121
Issue number3
DOIs
StatePublished - Mar 1 2011

Fingerprint

Angiofibroma
Blood Vessels
Angiography
Hemorrhage
Neoplasms
Nasopharynx
Tertiary Care Centers
Arteries

Keywords

  • Nasopharynx
  • angiofibroma
  • embolization
  • sinonasal tumors

ASJC Scopus subject areas

  • Otorhinolaryngology

Cite this

Wu, A. W., Mowry, S. E., Vinuela, F., Abemayor, E., & Wang, M. B. (2011). Bilateral vascular supply in juvenile nasopharyngeal angiofibromas. Laryngoscope, 121(3), 639-643. https://doi.org/10.1002/lary.21337

Bilateral vascular supply in juvenile nasopharyngeal angiofibromas. / Wu, Arthur W.; Mowry, Sarah E.; Vinuela, Fernando; Abemayor, Elliot; Wang, Marilene B.

In: Laryngoscope, Vol. 121, No. 3, 01.03.2011, p. 639-643.

Research output: Contribution to journalArticle

Wu, AW, Mowry, SE, Vinuela, F, Abemayor, E & Wang, MB 2011, 'Bilateral vascular supply in juvenile nasopharyngeal angiofibromas', Laryngoscope, vol. 121, no. 3, pp. 639-643. https://doi.org/10.1002/lary.21337
Wu AW, Mowry SE, Vinuela F, Abemayor E, Wang MB. Bilateral vascular supply in juvenile nasopharyngeal angiofibromas. Laryngoscope. 2011 Mar 1;121(3):639-643. https://doi.org/10.1002/lary.21337
Wu, Arthur W. ; Mowry, Sarah E. ; Vinuela, Fernando ; Abemayor, Elliot ; Wang, Marilene B. / Bilateral vascular supply in juvenile nasopharyngeal angiofibromas. In: Laryngoscope. 2011 ; Vol. 121, No. 3. pp. 639-643.
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