Biomimetic silicification of demineralized hierarchical collagenous tissues

Li Na Niu, Kai Jiao, Heonjune Ryou, Anibal Diogenes, Cynthia K.Y. Yiu, Annalisa Mazzoni, Ji Hua Chen, Dwayne D. Arola, Kenneth M. Hargreaves, David H. Pashley, Franklin R. Tay

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Unlike man-made composite materials, natural biominerals containing composites usually demonstrate different levels of sophisticated hierarchical structures which are responsible for their mechanical properties and other metabolic functions. However, the complex spatial organizations of the organic-inorganic phases are far beyond what they achieved by contemporary engineering techniques. Here, we demonstrate that carbonated apatite present in collagen matrices derived from fish scale and bovine bone may be replaced by amorphous silica, using an approach that simulates what is utilized by phylogenetically ancient glass sponges. The structural hierarchy of these collagen-based biomaterials is replicated by the infiltration and condensation of fluidic polymer-stabilized silicic acid precursors within the intrafibrillar milieu of type I collagen fibrils. This facile biomimetic silicification strategy may be used for fabricating silica-based, three-dimensional functional materials with specific morphological and hierarchical requirements.

Original languageEnglish (US)
Pages (from-to)1661-1668
Number of pages8
JournalBiomacromolecules
Volume14
Issue number5
DOIs
StatePublished - May 13 2013

Fingerprint

Biomimetics
Collagen
Silicon Dioxide
Silicic Acid
Tissue
Apatites
Functional materials
Composite materials
Fluidics
Biocompatible Materials
Collagen Type I
Silica
Infiltration
Fish
Condensation
Polymers
Bone
Apatite
Biomaterials
Glass

ASJC Scopus subject areas

  • Bioengineering
  • Biomaterials
  • Polymers and Plastics
  • Materials Chemistry

Cite this

Niu, L. N., Jiao, K., Ryou, H., Diogenes, A., Yiu, C. K. Y., Mazzoni, A., ... Tay, F. R. (2013). Biomimetic silicification of demineralized hierarchical collagenous tissues. Biomacromolecules, 14(5), 1661-1668. https://doi.org/10.1021/bm400316e

Biomimetic silicification of demineralized hierarchical collagenous tissues. / Niu, Li Na; Jiao, Kai; Ryou, Heonjune; Diogenes, Anibal; Yiu, Cynthia K.Y.; Mazzoni, Annalisa; Chen, Ji Hua; Arola, Dwayne D.; Hargreaves, Kenneth M.; Pashley, David H.; Tay, Franklin R.

In: Biomacromolecules, Vol. 14, No. 5, 13.05.2013, p. 1661-1668.

Research output: Contribution to journalArticle

Niu, LN, Jiao, K, Ryou, H, Diogenes, A, Yiu, CKY, Mazzoni, A, Chen, JH, Arola, DD, Hargreaves, KM, Pashley, DH & Tay, FR 2013, 'Biomimetic silicification of demineralized hierarchical collagenous tissues', Biomacromolecules, vol. 14, no. 5, pp. 1661-1668. https://doi.org/10.1021/bm400316e
Niu LN, Jiao K, Ryou H, Diogenes A, Yiu CKY, Mazzoni A et al. Biomimetic silicification of demineralized hierarchical collagenous tissues. Biomacromolecules. 2013 May 13;14(5):1661-1668. https://doi.org/10.1021/bm400316e
Niu, Li Na ; Jiao, Kai ; Ryou, Heonjune ; Diogenes, Anibal ; Yiu, Cynthia K.Y. ; Mazzoni, Annalisa ; Chen, Ji Hua ; Arola, Dwayne D. ; Hargreaves, Kenneth M. ; Pashley, David H. ; Tay, Franklin R. / Biomimetic silicification of demineralized hierarchical collagenous tissues. In: Biomacromolecules. 2013 ; Vol. 14, No. 5. pp. 1661-1668.
@article{cb069afd7f404830b936337244c32d1e,
title = "Biomimetic silicification of demineralized hierarchical collagenous tissues",
abstract = "Unlike man-made composite materials, natural biominerals containing composites usually demonstrate different levels of sophisticated hierarchical structures which are responsible for their mechanical properties and other metabolic functions. However, the complex spatial organizations of the organic-inorganic phases are far beyond what they achieved by contemporary engineering techniques. Here, we demonstrate that carbonated apatite present in collagen matrices derived from fish scale and bovine bone may be replaced by amorphous silica, using an approach that simulates what is utilized by phylogenetically ancient glass sponges. The structural hierarchy of these collagen-based biomaterials is replicated by the infiltration and condensation of fluidic polymer-stabilized silicic acid precursors within the intrafibrillar milieu of type I collagen fibrils. This facile biomimetic silicification strategy may be used for fabricating silica-based, three-dimensional functional materials with specific morphological and hierarchical requirements.",
author = "Niu, {Li Na} and Kai Jiao and Heonjune Ryou and Anibal Diogenes and Yiu, {Cynthia K.Y.} and Annalisa Mazzoni and Chen, {Ji Hua} and Arola, {Dwayne D.} and Hargreaves, {Kenneth M.} and Pashley, {David H.} and Tay, {Franklin R.}",
year = "2013",
month = "5",
day = "13",
doi = "10.1021/bm400316e",
language = "English (US)",
volume = "14",
pages = "1661--1668",
journal = "Biomacromolecules",
issn = "1525-7797",
publisher = "American Chemical Society",
number = "5",

}

TY - JOUR

T1 - Biomimetic silicification of demineralized hierarchical collagenous tissues

AU - Niu, Li Na

AU - Jiao, Kai

AU - Ryou, Heonjune

AU - Diogenes, Anibal

AU - Yiu, Cynthia K.Y.

AU - Mazzoni, Annalisa

AU - Chen, Ji Hua

AU - Arola, Dwayne D.

AU - Hargreaves, Kenneth M.

AU - Pashley, David H.

AU - Tay, Franklin R.

PY - 2013/5/13

Y1 - 2013/5/13

N2 - Unlike man-made composite materials, natural biominerals containing composites usually demonstrate different levels of sophisticated hierarchical structures which are responsible for their mechanical properties and other metabolic functions. However, the complex spatial organizations of the organic-inorganic phases are far beyond what they achieved by contemporary engineering techniques. Here, we demonstrate that carbonated apatite present in collagen matrices derived from fish scale and bovine bone may be replaced by amorphous silica, using an approach that simulates what is utilized by phylogenetically ancient glass sponges. The structural hierarchy of these collagen-based biomaterials is replicated by the infiltration and condensation of fluidic polymer-stabilized silicic acid precursors within the intrafibrillar milieu of type I collagen fibrils. This facile biomimetic silicification strategy may be used for fabricating silica-based, three-dimensional functional materials with specific morphological and hierarchical requirements.

AB - Unlike man-made composite materials, natural biominerals containing composites usually demonstrate different levels of sophisticated hierarchical structures which are responsible for their mechanical properties and other metabolic functions. However, the complex spatial organizations of the organic-inorganic phases are far beyond what they achieved by contemporary engineering techniques. Here, we demonstrate that carbonated apatite present in collagen matrices derived from fish scale and bovine bone may be replaced by amorphous silica, using an approach that simulates what is utilized by phylogenetically ancient glass sponges. The structural hierarchy of these collagen-based biomaterials is replicated by the infiltration and condensation of fluidic polymer-stabilized silicic acid precursors within the intrafibrillar milieu of type I collagen fibrils. This facile biomimetic silicification strategy may be used for fabricating silica-based, three-dimensional functional materials with specific morphological and hierarchical requirements.

UR - http://www.scopus.com/inward/record.url?scp=84877772844&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84877772844&partnerID=8YFLogxK

U2 - 10.1021/bm400316e

DO - 10.1021/bm400316e

M3 - Article

C2 - 23586938

AN - SCOPUS:84877772844

VL - 14

SP - 1661

EP - 1668

JO - Biomacromolecules

JF - Biomacromolecules

SN - 1525-7797

IS - 5

ER -