Blepharochalasis: something to cry about

Richard J. Browning, April T. Sanchez, Stephen Mullins, Daniel J. Sheehan, Loretta S. Davis

Research output: Contribution to journalArticle

2 Scopus citations

Abstract

Blepharochalasis is a rare disorder of unknown etiology defined by loose, atrophic periorbital skin following recurrent episodes of eyelid edema. Characteristic histopathology shows complete absence of elastic fibers. The current case progressed after multiple episodes of crying, which may be related to matrix metalloproteinase dysregulation. This case offers further insights into the possible pathogenesis of blepharochalasis, paving the way for more targeted, disease-modifying therapies.

Original languageEnglish (US)
Pages (from-to)279-282
Number of pages4
JournalJournal of Cutaneous Pathology
Volume44
Issue number3
DOIs
StatePublished - Mar 1 2017

Keywords

  • MMP
  • blepharochalasis
  • crying
  • matrix metalloproteinase

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Histology
  • Dermatology

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    Browning, R. J., Sanchez, A. T., Mullins, S., Sheehan, D. J., & Davis, L. S. (2017). Blepharochalasis: something to cry about. Journal of Cutaneous Pathology, 44(3), 279-282. https://doi.org/10.1111/cup.12841