Blepharochalasis: something to cry about

Richard J. Browning; April T. Sanchez; Stephen Mullins; Daniel J. Sheehan; Loretta S. Davis

doi:10.1111/cup.12841

Blepharochalasis: something to cry about

Richard J. Browning, April T. Sanchez, Stephen Mullins, Daniel J. Sheehan, Loretta S. Davis

Dermatology

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

Blepharochalasis is a rare disorder of unknown etiology defined by loose, atrophic periorbital skin following recurrent episodes of eyelid edema. Characteristic histopathology shows complete absence of elastic fibers. The current case progressed after multiple episodes of crying, which may be related to matrix metalloproteinase dysregulation. This case offers further insights into the possible pathogenesis of blepharochalasis, paving the way for more targeted, disease-modifying therapies.

Original language	English (US)
Pages (from-to)	279-282
Number of pages	4
Journal	Journal of Cutaneous Pathology
Volume	44
Issue number	3
DOIs	https://doi.org/10.1111/cup.12841
State	Published - Mar 1 2017

Keywords

MMP
blepharochalasis
crying
matrix metalloproteinase

ASJC Scopus subject areas

Pathology and Forensic Medicine
Histology
Dermatology

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10.1111/cup.12841

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title = "Blepharochalasis: something to cry about",

abstract = "Blepharochalasis is a rare disorder of unknown etiology defined by loose, atrophic periorbital skin following recurrent episodes of eyelid edema. Characteristic histopathology shows complete absence of elastic fibers. The current case progressed after multiple episodes of crying, which may be related to matrix metalloproteinase dysregulation. This case offers further insights into the possible pathogenesis of blepharochalasis, paving the way for more targeted, disease-modifying therapies.",

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author = "Browning, {Richard J.} and Sanchez, {April T.} and Stephen Mullins and Sheehan, {Daniel J.} and Davis, {Loretta S.}",

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AU - Browning, Richard J.

AU - Sanchez, April T.

AU - Mullins, Stephen

AU - Sheehan, Daniel J.

AU - Davis, Loretta S.

PY - 2017/3/1

Y1 - 2017/3/1

N2 - Blepharochalasis is a rare disorder of unknown etiology defined by loose, atrophic periorbital skin following recurrent episodes of eyelid edema. Characteristic histopathology shows complete absence of elastic fibers. The current case progressed after multiple episodes of crying, which may be related to matrix metalloproteinase dysregulation. This case offers further insights into the possible pathogenesis of blepharochalasis, paving the way for more targeted, disease-modifying therapies.

AB - Blepharochalasis is a rare disorder of unknown etiology defined by loose, atrophic periorbital skin following recurrent episodes of eyelid edema. Characteristic histopathology shows complete absence of elastic fibers. The current case progressed after multiple episodes of crying, which may be related to matrix metalloproteinase dysregulation. This case offers further insights into the possible pathogenesis of blepharochalasis, paving the way for more targeted, disease-modifying therapies.

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KW - matrix metalloproteinase

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Blepharochalasis: something to cry about

Abstract

Keywords

ASJC Scopus subject areas

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