Bone Morphogenetic Proteins

A Realistic Alternative to Bone Grafting for Alveolar Reconstruction

Ulf M E Wikesjö, Yi Hao Huang, Giuseppe Polimeni, Mohammed Qahash

Research output: Contribution to journalReview article

29 Citations (Scopus)

Abstract

Preclinical studies have shown that rhBMP-2 induces normal physiologic bone in clinically relevant defects in the craniofacial skeleton. The newly formed bone assumes characteristics of the adjacent resident bone and allows placement, osseointegration/re-osseointegration, and functional loading of endosseous implants. Clinical studies optimizing dose, delivery technologies, and conditions for stimulation of bone growth will bring about a new era in dentistry. The ability to predictably promote osteogenesis through the use of bone morphogenetic protein technologies is not far from becoming a clinical reality and will have an astounding effect on how dentistry is practiced.

Original languageEnglish (US)
Pages (from-to)535-551
Number of pages17
JournalOral and Maxillofacial Surgery Clinics of North America
Volume19
Issue number4
DOIs
StatePublished - Nov 1 2007

Fingerprint

Alveolar Bone Grafting
Bone Morphogenetic Proteins
Staphylococcal Protein A
Osseointegration
Dentistry
Bone and Bones
Technology
Bone Development
Osteogenesis
Skeleton

ASJC Scopus subject areas

  • Surgery
  • Dentistry(all)

Cite this

Bone Morphogenetic Proteins : A Realistic Alternative to Bone Grafting for Alveolar Reconstruction. / Wikesjö, Ulf M E; Huang, Yi Hao; Polimeni, Giuseppe; Qahash, Mohammed.

In: Oral and Maxillofacial Surgery Clinics of North America, Vol. 19, No. 4, 01.11.2007, p. 535-551.

Research output: Contribution to journalReview article

Wikesjö, Ulf M E ; Huang, Yi Hao ; Polimeni, Giuseppe ; Qahash, Mohammed. / Bone Morphogenetic Proteins : A Realistic Alternative to Bone Grafting for Alveolar Reconstruction. In: Oral and Maxillofacial Surgery Clinics of North America. 2007 ; Vol. 19, No. 4. pp. 535-551.
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