TY - JOUR
T1 - Bread mold infection in diabetes. The life-threatening condition of rhinocerebral zygomycosis
AU - Oakley, L. A.
AU - Fisher, John Fremont
AU - Dennison, Jacquelyn Hammond
PY - 1986/1/1
Y1 - 1986/1/1
N2 - Rhinocerebral zygomycosis is a rare but dangerous fungal infection that affects primarily diabetic patients in ketoacidosis but other debilitated patients as well. A high index of suspicion among primary care physicians will lead to earlier diagnosis and help reduce the severe morbidity and mortality associated with the condition. Zygomycosis should be strongly suspected in diabetic patients presenting with unilateral headache, nasal congestion, or facial pain and swelling. If hyphae are not seen in nasal secretions on microscopy, biopsy of infected tissue must be done immediately to establish a diagnosis. Prompt treatment, including appropriate surgical intervention, amphotericin B therapy, and correction of metabolic derangements, is essential.
AB - Rhinocerebral zygomycosis is a rare but dangerous fungal infection that affects primarily diabetic patients in ketoacidosis but other debilitated patients as well. A high index of suspicion among primary care physicians will lead to earlier diagnosis and help reduce the severe morbidity and mortality associated with the condition. Zygomycosis should be strongly suspected in diabetic patients presenting with unilateral headache, nasal congestion, or facial pain and swelling. If hyphae are not seen in nasal secretions on microscopy, biopsy of infected tissue must be done immediately to establish a diagnosis. Prompt treatment, including appropriate surgical intervention, amphotericin B therapy, and correction of metabolic derangements, is essential.
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U2 - 10.1080/00325481.1986.11699485
DO - 10.1080/00325481.1986.11699485
M3 - Review article
C2 - 3090535
AN - SCOPUS:0022504201
SN - 0032-5481
VL - 80
SP - 93
EP - 102
JO - Postgraduate Medicine
JF - Postgraduate Medicine
IS - 2
ER -