Caged Q-rhodamine dextran: A new photoactivated fluorescent tracer

Kyle R. Gee, Eric S. Weinberg, David J. Kozlowski

Research output: Contribution to journalArticlepeer-review

57 Scopus citations

Abstract

An amine-reactive caged rhodamine was synthesized and conjugated to aminodextran. The resulting tracer was injected into a single cell zebrafish embryo, and a portion of the tracer was photolyzed in a single cell after development. The resulting fluorescent cell was imaged by fluorescence microscopy through a single round of cell division.

Original languageEnglish (US)
Pages (from-to)2181-2183
Number of pages3
JournalBioorganic and Medicinal Chemistry Letters
Volume11
Issue number16
DOIs
StatePublished - Aug 20 2001
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Medicine
  • Molecular Biology
  • Pharmaceutical Science
  • Drug Discovery
  • Clinical Biochemistry
  • Organic Chemistry

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