Candida glabrata: An important fungal pathogen for the 21st century

Paul L. Fidel, Jose A. Vazquez, Jack D. Sobel

Research output: Contribution to journalArticle

4 Scopus citations

Abstract

Although Candida glabrata has been viewed as a relatively nonpathogenic saprophyte, it is now considered an important fungal pathogen. The reason is the widespread use of immunosuppressive therapy, together with broad-spectrum antimycotic therapy to which the organism may be resistant. This article reviews the biology, epidemiology, pathogenesis, clinical spectrum of infection, and antifungal resistance of this yeast. Infections with C. glabrata are likely to increase as antifungal agents continue to be used; therefore, further studies of pathogenesis, host responses, and antifungal resistance mechanisms are needed.

Original languageEnglish (US)
Pages (from-to)171-176
Number of pages6
JournalClinical Microbiology Newsletter
Volume23
Issue number22
DOIs
StatePublished - Nov 15 2001
Externally publishedYes

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

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