Carcinoma of type II pneumocytes. PAS staining as a screening test for nuclear inclusions of surfactant specific apoprotein

Gurmukh Singh, Sikandar L. Katyal, Chikao Torikata

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

Bronchioloalveolar carcinomas (n = 15) and other primary lung carcinomas (n = 9) were studied by PAS staining. The bronchioloalveolar carcinoma group contained three cases of carcinomas of type II pneumocytes. Cytoplasmic staining with PAS was most intense in mucus secreting carcinomas. Carcinomas of type II pneumocytes could not be differentiated from other tumors on the basis of cytoplasmic PAS staining. However, PAS positive nuclear “inclusion” were seen only in the three carcinomas of type II pneumocytes. The study indicates that PAS staining, though nonspecific, may serve as a screening test for carcinomas of type II pneumocytes by highlighting the nuclear inclusions of surfactant specific apoprotein.

Original languageEnglish (US)
Pages (from-to)946-948
Number of pages3
JournalCancer
Volume50
Issue number5
DOIs
StatePublished - Jan 1 1982

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Alveolar Epithelial Cells
Intranuclear Inclusion Bodies
Apoproteins
Surface-Active Agents
Staining and Labeling
Carcinoma
Bronchiolo-Alveolar Adenocarcinoma
Mucus
Lung
Neoplasms

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

Cite this

Carcinoma of type II pneumocytes. PAS staining as a screening test for nuclear inclusions of surfactant specific apoprotein. / Singh, Gurmukh; Katyal, Sikandar L.; Torikata, Chikao.

In: Cancer, Vol. 50, No. 5, 01.01.1982, p. 946-948.

Research output: Contribution to journalArticle

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