Cardiac Resynchronization Therapy for Heart Failure

Amole Ojo, Sohaib Tariq, Prakash Harikrishnan, Sei Iwai, Jason T. Jacobson

Research output: Contribution to journalReview article

1 Scopus citations

Abstract

Cardiac resynchronization therapy (CRT) has emerged as a valued nonpharmacologic therapy in patients with heart failure, reduced ejection fraction (EF), and ventricular dyssynchrony manifest as left bundle branch block. The mechanisms of benefit include remodeling of the left ventricle leading to decreased dimensions and increased EF, as well as a decrease in the severity of mitral regurgitation. This article reviews the rationale, effects, and indications for CRT, and discusses the patient characteristics that predict response and considerations for nonresponders.

Original languageEnglish (US)
Pages (from-to)417-426
Number of pages10
JournalInterventional Cardiology Clinics
Volume6
Issue number3
DOIs
StatePublished - Jul 2017
Externally publishedYes

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Keywords

  • Biventricular pacing
  • Cardiac resynchronization therapy
  • Dyssynchrony
  • Heart failure with reduced ejection fraction

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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