Case 8-1993: Cysticercosis

Oscar H. Del Brutto, James H. Maguire, John W. Henson

Research output: Contribution to journalLetterpeer-review

1 Scopus citations

Abstract

To the Editor: Case 8-1993 (Feb. 25 issue)1 describes a patient with subarachnoid cysticercosis who was treated with praziquantel without the simultaneous administration of glucocorticoids. This approach contrasts with that currently recommended for the management of this form of the disease2. Although both praziquantel and albendazole are effective against parenchymal brain cysticerci, the latter is the drug of choice for subarachnoid cysts3. Albendazole and praziquantel have different mechanisms of action. Praziquantel destroys the scolex of the cysticercus by producing spastic paralysis of the parasite's musculature. In contrast, albendazole inhibits the uptake of glucose by parasitic membranes, causing energy…

Original languageEnglish (US)
Pages (from-to)813
Number of pages1
JournalNew England Journal of Medicine
Volume329
Issue number11
DOIs
StatePublished - Sep 9 1993
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)

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