TY - JOUR
T1 - Case report
T2 - A pregnant woman with immune thrombocytopenic purpura and unusual red cell antibodies
AU - Nanton, C. R.
AU - Martin, S. M.
AU - Cook, L. O.
AU - Larison, P. J.
N1 - Publisher Copyright:
© 1995 American Red Cross. All rights reserved.
PY - 1995
Y1 - 1995
N2 - Maternal immune thrombocytopenic purpura (ITP) may lead to fetal platelet destruction. This process is mediated by IgG platelet autoantibodies that cross the placenta. In this case, not only were platelet autoantibodies present, but red cell alloantibodies anti-E, anti-M, and anti-He were also present. Anti-E, present as an IgG antibody, crossed the placenta, but did not cause clinical problems in the E+ newborn, other than possible hyperbilirubinemia that was treated by phototherapy.
AB - Maternal immune thrombocytopenic purpura (ITP) may lead to fetal platelet destruction. This process is mediated by IgG platelet autoantibodies that cross the placenta. In this case, not only were platelet autoantibodies present, but red cell alloantibodies anti-E, anti-M, and anti-He were also present. Anti-E, present as an IgG antibody, crossed the placenta, but did not cause clinical problems in the E+ newborn, other than possible hyperbilirubinemia that was treated by phototherapy.
UR - http://www.scopus.com/inward/record.url?scp=0028785875&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0028785875&partnerID=8YFLogxK
U2 - 10.21307/IMMUNOHEMATOLOGY-2019-808
DO - 10.21307/IMMUNOHEMATOLOGY-2019-808
M3 - Article
C2 - 15447058
AN - SCOPUS:0028785875
SN - 0894-203X
VL - 11
SP - 153
EP - 155
JO - Immunohematology / American Red Cross
JF - Immunohematology / American Red Cross
IS - 4
ER -