Case report: Castleman disease in association with POEMS

H. M. Adelman, M. L. Cacciatore, J. F. Pascual, J. M. Mike, W. M. Alberts, Paul M Wallach

Research output: Contribution to journalArticle

34 Citations (Scopus)

Abstract

Castleman disease, or angiofollicular lymph node hyperplasia, and POEMS (Polyneuropathy, Organomegaly, Endocrinopathy, Monoclonal gammopathy, and Skin changes), are associated and can lead to a clinical conundrum. The physician caring for a patient with Castleman disease should be alert to the development of multiple endocrine deficiencies, including primary hypogonadism, diabetes mellitus, hypothyroidism, and adrenal insufficiency. Avoidance of treating hypothyroidism alone when there is concomitant subclinical adrenal insufficiency is important, to avoid precipitating an adrenal crisis. A better outcome may result from earlier recognition of the endocrinopathies of this syndrome. This article describes a patient with Castleman disease in whom the features of POEMS unfolded over the ensuing years.

Original languageEnglish (US)
Pages (from-to)112-114
Number of pages3
JournalAmerican Journal of the Medical Sciences
Volume307
Issue number2
DOIs
StatePublished - Jan 1 1994

Fingerprint

POEMS Syndrome
Giant Lymph Node Hyperplasia
Paraproteinemias
Adrenal Insufficiency
Skin
Hypothyroidism
Hypogonadism
Diabetes Mellitus
Physicians

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Adelman, H. M., Cacciatore, M. L., Pascual, J. F., Mike, J. M., Alberts, W. M., & Wallach, P. M. (1994). Case report: Castleman disease in association with POEMS. American Journal of the Medical Sciences, 307(2), 112-114. https://doi.org/10.1097/00000441-199402000-00008

Case report : Castleman disease in association with POEMS. / Adelman, H. M.; Cacciatore, M. L.; Pascual, J. F.; Mike, J. M.; Alberts, W. M.; Wallach, Paul M.

In: American Journal of the Medical Sciences, Vol. 307, No. 2, 01.01.1994, p. 112-114.

Research output: Contribution to journalArticle

Adelman, HM, Cacciatore, ML, Pascual, JF, Mike, JM, Alberts, WM & Wallach, PM 1994, 'Case report: Castleman disease in association with POEMS', American Journal of the Medical Sciences, vol. 307, no. 2, pp. 112-114. https://doi.org/10.1097/00000441-199402000-00008
Adelman HM, Cacciatore ML, Pascual JF, Mike JM, Alberts WM, Wallach PM. Case report: Castleman disease in association with POEMS. American Journal of the Medical Sciences. 1994 Jan 1;307(2):112-114. https://doi.org/10.1097/00000441-199402000-00008
Adelman, H. M. ; Cacciatore, M. L. ; Pascual, J. F. ; Mike, J. M. ; Alberts, W. M. ; Wallach, Paul M. / Case report : Castleman disease in association with POEMS. In: American Journal of the Medical Sciences. 1994 ; Vol. 307, No. 2. pp. 112-114.
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