Caspase-3, shears for synapse pruning

Chengyong Shen, Wencheng Xiong, Lin Mei

Research output: Contribution to journalShort survey

3 Scopus citations

Abstract

Motor neurons regulate neuromuscular junction formation by using agrin to stimulate acetylcholine receptor clustering and using acetylcholine to disperse unnecessary receptor clusters on muscle fibers. Wang etal. (2014) now report in this issue of Developmental Cell a critical role for caspase-3 in intracellular mechanisms of acetylcholine-induced dispersal.

Original languageEnglish (US)
Pages (from-to)604-606
Number of pages3
JournalDevelopmental Cell
Volume28
Issue number6
DOIs
StatePublished - Mar 31 2014

ASJC Scopus subject areas

  • Molecular Biology
  • Biochemistry, Genetics and Molecular Biology(all)
  • Developmental Biology
  • Cell Biology

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