Caspase-3, shears for synapse pruning

Chengyong Shen, Wencheng Xiong, Lin Mei

Research output: Contribution to journalShort survey

2 Citations (Scopus)

Abstract

Motor neurons regulate neuromuscular junction formation by using agrin to stimulate acetylcholine receptor clustering and using acetylcholine to disperse unnecessary receptor clusters on muscle fibers. Wang etal. (2014) now report in this issue of Developmental Cell a critical role for caspase-3 in intracellular mechanisms of acetylcholine-induced dispersal.

Original languageEnglish (US)
Pages (from-to)604-606
Number of pages3
JournalDevelopmental Cell
Volume28
Issue number6
DOIs
StatePublished - Mar 31 2014

Fingerprint

Caspase 3
Synapses
Acetylcholine
Agrin
Neuromuscular Junction
Motor Neurons
Cholinergic Receptors
Neurons
Cluster Analysis
Muscle
Muscles
Fibers

ASJC Scopus subject areas

  • Developmental Biology
  • Medicine(all)

Cite this

Caspase-3, shears for synapse pruning. / Shen, Chengyong; Xiong, Wencheng; Mei, Lin.

In: Developmental Cell, Vol. 28, No. 6, 31.03.2014, p. 604-606.

Research output: Contribution to journalShort survey

Shen, C, Xiong, W & Mei, L 2014, 'Caspase-3, shears for synapse pruning', Developmental Cell, vol. 28, no. 6, pp. 604-606. https://doi.org/10.1016/j.devcel.2014.03.010
Shen, Chengyong ; Xiong, Wencheng ; Mei, Lin. / Caspase-3, shears for synapse pruning. In: Developmental Cell. 2014 ; Vol. 28, No. 6. pp. 604-606.
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