Caspase-3, shears for synapse pruning

Chengyong Shen, Wen C. Xiong, Lin Mei

Research output: Contribution to journalShort surveypeer-review

5 Scopus citations


Motor neurons regulate neuromuscular junction formation by using agrin to stimulate acetylcholine receptor clustering and using acetylcholine to disperse unnecessary receptor clusters on muscle fibers. Wang etal. (2014) now report in this issue of Developmental Cell a critical role for caspase-3 in intracellular mechanisms of acetylcholine-induced dispersal.

Original languageEnglish (US)
Pages (from-to)604-606
Number of pages3
JournalDevelopmental Cell
Issue number6
StatePublished - Mar 31 2014
Externally publishedYes

ASJC Scopus subject areas

  • Molecular Biology
  • Biochemistry, Genetics and Molecular Biology(all)
  • Developmental Biology
  • Cell Biology


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