Caspofungin

P. H. Chandrasekar, E. K. Manavathu

Research output: Contribution to journalReview article

17 Scopus citations

Abstract

Available systemically effective antifungal agents for the treatment of invasive fungal infections are few. With the increasing recognition of a need for newer antifungal drugs, caspofungin has been introduced as the first member of a new class of compounds called echinocandins. This paper reviews the chemistry and mechanism of action of caspofungin, its activity in vitro and in animal models, and clinical pharmacokinetics, clinical efficacy and safety in patients.

Original languageEnglish (US)
Pages (from-to)829-846
Number of pages18
JournalDrugs of Today
Volume38
Issue number12
DOIs
StatePublished - Dec 1 2002

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)

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    Chandrasekar, P. H., & Manavathu, E. K. (2002). Caspofungin. Drugs of Today, 38(12), 829-846. https://doi.org/10.1358/dot.2002.38.12.820101