Caspofungin

P. H. Chandrasekar, E. K. Manavathu

Research output: Contribution to journalReview article

17 Citations (Scopus)

Abstract

Available systemically effective antifungal agents for the treatment of invasive fungal infections are few. With the increasing recognition of a need for newer antifungal drugs, caspofungin has been introduced as the first member of a new class of compounds called echinocandins. This paper reviews the chemistry and mechanism of action of caspofungin, its activity in vitro and in animal models, and clinical pharmacokinetics, clinical efficacy and safety in patients.

Original languageEnglish (US)
Pages (from-to)829-846
Number of pages18
JournalDrugs of Today
Volume38
Issue number12
DOIs
StatePublished - Dec 1 2002

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caspofungin
Echinocandins
Antifungal Agents
Patient Safety
Animal Models
Pharmacokinetics
Pharmaceutical Preparations

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)

Cite this

Chandrasekar, P. H., & Manavathu, E. K. (2002). Caspofungin. Drugs of Today, 38(12), 829-846. https://doi.org/10.1358/dot.2002.38.12.820101

Caspofungin. / Chandrasekar, P. H.; Manavathu, E. K.

In: Drugs of Today, Vol. 38, No. 12, 01.12.2002, p. 829-846.

Research output: Contribution to journalReview article

Chandrasekar, PH & Manavathu, EK 2002, 'Caspofungin', Drugs of Today, vol. 38, no. 12, pp. 829-846. https://doi.org/10.1358/dot.2002.38.12.820101
Chandrasekar PH, Manavathu EK. Caspofungin. Drugs of Today. 2002 Dec 1;38(12):829-846. https://doi.org/10.1358/dot.2002.38.12.820101
Chandrasekar, P. H. ; Manavathu, E. K. / Caspofungin. In: Drugs of Today. 2002 ; Vol. 38, No. 12. pp. 829-846.
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