Central role of insulin in growth and development

Roy J. Martin, T. G. Ramsay, Ruth Babette Harris

Research output: Contribution to journalReview article

5 Citations (Scopus)

Abstract

Insulin has been shown to have an impact on both prenatal and postnatal growth. Specific mechanisms of insulin action on adipose cell function and lipid storage are well defined. Insulin probably acts in concert with other anabolic factors (i.e., growth hormone and somatomedins) to stimulate muscle protein anabolism and suppress protein catabolism (Figure 2). Insulin also plays a role in energy balance regulation by the hypothalamus, however exact mechanisms of effects on brain metabolism have not been clearly identified.

Original languageEnglish (US)
Pages (from-to)89-104
Number of pages16
JournalDomestic Animal Endocrinology
Volume1
Issue number2
DOIs
StatePublished - Jan 1 1984
Externally publishedYes

Fingerprint

Growth and Development
growth and development
insulin
Insulin
Muscle Proteins
muscle protein
somatomedins
Somatomedins
hypothalamus
protein metabolism
energy balance
somatotropin
Growth Hormone
Hypothalamus
protein synthesis
brain
Lipids
metabolism
Brain
lipids

ASJC Scopus subject areas

  • Food Animals
  • Animal Science and Zoology
  • Endocrinology

Cite this

Central role of insulin in growth and development. / Martin, Roy J.; Ramsay, T. G.; Harris, Ruth Babette.

In: Domestic Animal Endocrinology, Vol. 1, No. 2, 01.01.1984, p. 89-104.

Research output: Contribution to journalReview article

Martin, Roy J. ; Ramsay, T. G. ; Harris, Ruth Babette. / Central role of insulin in growth and development. In: Domestic Animal Endocrinology. 1984 ; Vol. 1, No. 2. pp. 89-104.
@article{fb7c243534a04e049b78791d72a3eba6,
title = "Central role of insulin in growth and development",
abstract = "Insulin has been shown to have an impact on both prenatal and postnatal growth. Specific mechanisms of insulin action on adipose cell function and lipid storage are well defined. Insulin probably acts in concert with other anabolic factors (i.e., growth hormone and somatomedins) to stimulate muscle protein anabolism and suppress protein catabolism (Figure 2). Insulin also plays a role in energy balance regulation by the hypothalamus, however exact mechanisms of effects on brain metabolism have not been clearly identified.",
author = "Martin, {Roy J.} and Ramsay, {T. G.} and Harris, {Ruth Babette}",
year = "1984",
month = "1",
day = "1",
doi = "10.1016/0739-7240(84)90024-9",
language = "English (US)",
volume = "1",
pages = "89--104",
journal = "Domestic Animal Endocrinology",
issn = "0739-7240",
publisher = "Elsevier Inc.",
number = "2",

}

TY - JOUR

T1 - Central role of insulin in growth and development

AU - Martin, Roy J.

AU - Ramsay, T. G.

AU - Harris, Ruth Babette

PY - 1984/1/1

Y1 - 1984/1/1

N2 - Insulin has been shown to have an impact on both prenatal and postnatal growth. Specific mechanisms of insulin action on adipose cell function and lipid storage are well defined. Insulin probably acts in concert with other anabolic factors (i.e., growth hormone and somatomedins) to stimulate muscle protein anabolism and suppress protein catabolism (Figure 2). Insulin also plays a role in energy balance regulation by the hypothalamus, however exact mechanisms of effects on brain metabolism have not been clearly identified.

AB - Insulin has been shown to have an impact on both prenatal and postnatal growth. Specific mechanisms of insulin action on adipose cell function and lipid storage are well defined. Insulin probably acts in concert with other anabolic factors (i.e., growth hormone and somatomedins) to stimulate muscle protein anabolism and suppress protein catabolism (Figure 2). Insulin also plays a role in energy balance regulation by the hypothalamus, however exact mechanisms of effects on brain metabolism have not been clearly identified.

UR - http://www.scopus.com/inward/record.url?scp=0003376925&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0003376925&partnerID=8YFLogxK

U2 - 10.1016/0739-7240(84)90024-9

DO - 10.1016/0739-7240(84)90024-9

M3 - Review article

AN - SCOPUS:0003376925

VL - 1

SP - 89

EP - 104

JO - Domestic Animal Endocrinology

JF - Domestic Animal Endocrinology

SN - 0739-7240

IS - 2

ER -