Changes in pennate muscle architecture after gradual tibial lengthening in goats

Mohammed Elsalanty, Marina Makarov, Alexander Cherkashin, John Birch, Mikhail Samchukov

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

The purpose of this investigation was to examine the changes in unipennate muscle architecture after distraction osteogenesis. Nine adult goats underwent 20% tibial lengthening in one of the hind limbs. Immediately after distraction, lengthened and contralateral (untreated) tibialis caudalis (TC) muscles were harvested. Lengths of the muscle belly, muscle fiber (FL), sarcomere (SL), tendon (TL), and superficial aponeurosis, as well as muscle mass, pennation angle (PA), and physiological cross-sectional area (PCSA), were compared between the treated and contralateral sides. Lengthened TC muscle demonstrated 20.8% increase in belly length, 4.39% increase in TL, and 36.7% increase in FL, while PA decreased by 37.2% (P = 008). Muscle length increase was mainly due to lengthening of muscle belly, which resulted both from FL increase and 15.3% length increase in the aponeurosis component of muscle belly, without significant effect of the PA decrease. The FL increase was due to SL increase, not to sarcomere neogenesis, while mass and PCSA did not change. We concluded that although muscle architecture can be adversely affected by distraction because of deficient sarcomere neogenesis, PCSA can remain unchanged, giving false impression of preserved function. Change in PA plays only minimal role in muscle adaptation to distraction.

Original languageEnglish (US)
Pages (from-to)461-467
Number of pages7
JournalAnatomical Record
Volume290
Issue number5
DOIs
StatePublished - May 1 2007

Fingerprint

goat
Goats
muscle
goats
Muscles
muscles
sarcomeres
Sarcomeres
Distraction Osteogenesis
tendons
bone formation
limbs (animal)
muscle fibers
Tendons
limb
Extremities

Keywords

  • Adaptation
  • Architecture
  • Distraction
  • Goat
  • Muscle
  • Pennation
  • Sarcomere

ASJC Scopus subject areas

  • Anatomy
  • Biotechnology
  • Histology
  • Ecology, Evolution, Behavior and Systematics

Cite this

Changes in pennate muscle architecture after gradual tibial lengthening in goats. / Elsalanty, Mohammed; Makarov, Marina; Cherkashin, Alexander; Birch, John; Samchukov, Mikhail.

In: Anatomical Record, Vol. 290, No. 5, 01.05.2007, p. 461-467.

Research output: Contribution to journalArticle

Elsalanty, M, Makarov, M, Cherkashin, A, Birch, J & Samchukov, M 2007, 'Changes in pennate muscle architecture after gradual tibial lengthening in goats', Anatomical Record, vol. 290, no. 5, pp. 461-467. https://doi.org/10.1002/ar.20513
Elsalanty, Mohammed ; Makarov, Marina ; Cherkashin, Alexander ; Birch, John ; Samchukov, Mikhail. / Changes in pennate muscle architecture after gradual tibial lengthening in goats. In: Anatomical Record. 2007 ; Vol. 290, No. 5. pp. 461-467.
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