Chapter 4.1 Neural coding of episodic memory

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Recent identification of network-level organizing principle and memory-encoding units in the hippocampus has allowed real-time patterns of memory traces to be mathematically described, intuitively visualized, and dynamically deciphered. Any given episodic event is represented and encoded by the activation of a set of neural clique assemblies, which are organized in a categorical and hierarchical manner. This hierarchical feature-encoding pyramid is invariantly composed of the general feature-encoding clique at the bottom, subgeneral feature-encoding cliques in the middle, and highly specific feature-encoding cliques at the top. This hierarchical and categorical organization of neural clique assemblies provides the network-level mechanism the capability of not only achieving vast storage capacity, but also generating commonalities from the individual behavioral episodes and converting them to the abstract concepts and generalized knowledge that are essential for intelligence and adaptive behaviors. Furthermore, activation patterns of the neural clique assemblies can be mathematically converted to strings of binary codes that would permit universal categorizations of the brain's internal representations across individuals and species. Such universal brain codes can also potentially facilitate the unprecedented brain-machine-interface communications.

Original languageEnglish (US)
Title of host publicationHandbook of Episodic Memory
PublisherElsevier
ISBN (Print)9780444531742
DOIs
StatePublished - Jan 1 2008

Publication series

NameHandbook of Behavioral Neuroscience
Volume18
ISSN (Print)1569-7339

Fingerprint

Episodic Memory
Brain-Computer Interfaces
Psychological Adaptation
Brain
Intelligence
Hippocampus
Communication

Keywords

  • binary code
  • cell assembly
  • concept
  • declarative memory
  • ensemble recording
  • episodic memory
  • feature-encoding pyramid
  • hierarchical and categorical organization
  • hierarchical clustering method
  • hippocampus
  • knowledge
  • multiple discriminant analysis
  • neural clique
  • neural code
  • semantic memory

ASJC Scopus subject areas

  • Cognitive Neuroscience
  • Behavioral Neuroscience

Cite this

Tsien, J. Z. (2008). Chapter 4.1 Neural coding of episodic memory. In Handbook of Episodic Memory (Handbook of Behavioral Neuroscience; Vol. 18). Elsevier. https://doi.org/10.1016/S1569-7339(08)00222-1

Chapter 4.1 Neural coding of episodic memory. / Tsien, Joseph Zhuo.

Handbook of Episodic Memory. Elsevier, 2008. (Handbook of Behavioral Neuroscience; Vol. 18).

Research output: Chapter in Book/Report/Conference proceedingChapter

Tsien, JZ 2008, Chapter 4.1 Neural coding of episodic memory. in Handbook of Episodic Memory. Handbook of Behavioral Neuroscience, vol. 18, Elsevier. https://doi.org/10.1016/S1569-7339(08)00222-1
Tsien JZ. Chapter 4.1 Neural coding of episodic memory. In Handbook of Episodic Memory. Elsevier. 2008. (Handbook of Behavioral Neuroscience). https://doi.org/10.1016/S1569-7339(08)00222-1
Tsien, Joseph Zhuo. / Chapter 4.1 Neural coding of episodic memory. Handbook of Episodic Memory. Elsevier, 2008. (Handbook of Behavioral Neuroscience).
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