TY - JOUR
T1 - CHARACTERIZATION OF GLYCOSPHINGOLIPIDS BY FABMS.
AU - Hemling, Mark E.
AU - Sedgwick, R. Donald
AU - Rinehart, Kenneth L.
AU - Yu, Robert K
PY - 1984/12/1
Y1 - 1984/12/1
N2 - The growing interest in the diverse biological functions of cell membrane glycosphingolipids (GSL's) as cell surface antigens, cell-cell recognition sites, and receptors for a variety of signal molecules has prompted the constant search for new procedures for their structural analysis. Mass spectrometry, because of its high sensitivity and speed, has always figured prominently in this regard. This paper presents detailed systematic analysis of a number of GSL's of increasing complexity and their ceramides, using FAB mass spectrometry. High resolution measurements and linked scans are used to confirm fragmentations. Matrix requirements and homologous mixture analysis are also discussed.
AB - The growing interest in the diverse biological functions of cell membrane glycosphingolipids (GSL's) as cell surface antigens, cell-cell recognition sites, and receptors for a variety of signal molecules has prompted the constant search for new procedures for their structural analysis. Mass spectrometry, because of its high sensitivity and speed, has always figured prominently in this regard. This paper presents detailed systematic analysis of a number of GSL's of increasing complexity and their ceramides, using FAB mass spectrometry. High resolution measurements and linked scans are used to confirm fragmentations. Matrix requirements and homologous mixture analysis are also discussed.
UR - http://www.scopus.com/inward/record.url?scp=0021562188&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0021562188&partnerID=8YFLogxK
M3 - Conference article
AN - SCOPUS:0021562188
SN - 0739-5817
SP - 811
EP - 812
JO - Annual Conference on Mass Spectrometry and Allied Topics
JF - Annual Conference on Mass Spectrometry and Allied Topics
ER -