Chronic Cladribine Administration Increases Amyloid Beta Peptide Generation and Plaque Burden in Mice

Agriculture & Biology

• amyloid beta-peptides 80%
• amyloid 42%
• biotin 40%
• learning 33%
• animal models 32%
• mice 31%
• cis-trans isomerism 28%
• sclerosis 24%
• blood-brain barrier 24%
• Alzheimer disease 22%
• surface proteins 20%
• cycloheximide 18%
• cells 17%
• phosphorylation 15%
• adverse effects 14%
• neoplasms 13%
• secretion 12%
• brain 12%
• peptides 12%
• drugs 12%
• antibodies 12%
• proteins 6%
• methodology 4%

Chemical Compounds

• Cladribine 100%
• Beta-Amyloid 61%
• Peptide 31%
• Conditioned Culture Medium 27%
• Haematological 26%
• Biotin 19%
• Non Toxic 18%
• Surface 17%
• Protein 15%
• Isomerization 14%
• Plasma 11%
• Drug 9%

Medicine & Life Sciences

• 2'-deoxyadenosine 82%
• Cladribine 80%
• Amyloid beta-Peptides 61%
• Biotin 10%
• peptide A 7%
• Alzheimer disease type 2 7%
• Learning 7%
• CHO Cells 5%
• Cycloheximide 5%
• Amyloid Plaques 5%
• Conditioned Culture Medium 5%
• Immunoprecipitation 4%
• Blood-Brain Barrier 4%
• Reward 4%
• Amyloid 4%
• Multiple Sclerosis 4%
• Anti-Idiotypic Antibodies 4%
• Membrane Proteins 4%
• Animal Models 3%
• Phosphorylation 3%
• Brain 2%
• Pharmaceutical Preparations 2%
• Proteins 1%
• Therapeutics 1%
• Neoplasms 1%