Abstract
To determine the most suitable strategy in treating patients with invasive breast cancer from Northwest China. Lower recurrence score (RS) correlated with lower recurrence ratio. Patients having a medium-high 21-gene RS who received adjuvant therapy presented lower recurrence risk. Younger patients having RS results (⩾31) tended to accept adjuvant therapy more often, however, those having intermediate RS results were inclined to wait and did not receive chemotherapy. These results suggested that RS-based precision medicine will allow individualized diagnosis and treatment, resulting in better outcomes and preserved medical resources.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 639-646 |
| Number of pages | 8 |
| Journal | Cancer Investigation |
| Volume | 35 |
| Issue number | 10 |
| DOIs | |
| State | Published - Nov 26 2017 |
Keywords
- 21-Gene recurrence score
- Breast cancer
- Cancer stem cells
- Recurrence risk
ASJC Scopus subject areas
- Oncology
- Cancer Research
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Cite this
Xiao, G., Meng, J., Zhang, J., Li, G., Du, N., Qin, S., Wang, J., Xu, C., Ren, H., Tang, S-C., & Sun, X. (2017). Clinical Application of Detecting 21-Gene Recurrence Score in Predicating Prognosis and Therapy Response of Patients with Breast Cancer from Two Medical Centers. Cancer Investigation, 35(10), 639-646. https://doi.org/10.1080/07357907.2017.1405015