Abstract
The cDNA coding for GT3-synthase has been cloned from a rat fetal brain cDNA library. The complete nucleotide sequence and the deduced amino acid sequence of the rat GT3-synthase cDNA were highly homologous to those of the mouse GT3-synthase. Quantitative RT-PCR showed that, as a key enzyme for the synthesis of 'c'-series gangliosides, the expression of GT3-synthase was developmentally regulated in embryonic rat brains.
Original language | English (US) |
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Pages (from-to) | 131-134 |
Number of pages | 4 |
Journal | Gene |
Volume | 187 |
Issue number | 1 |
DOIs | |
State | Published - Mar 10 1997 |
Externally published | Yes |
Keywords
- GT3-synthase
- Gangliosides
- Gene expression
- Polymerase chain reaction
ASJC Scopus subject areas
- Genetics