Abstract
This study was undertaken to estimate the accuracy of colposcopy quality control review of subjects' digitized colposcopic images during the atypical squamous cells of undetermined significance/low-grade squamous intraepithelial lesion triage study (ALTS). After colposcopic examination and the acquisition of 2 digitized cervical images, colposcopists recorded colposcopic diagnoses in a standardized computer database. The images were transferred by modem to colposcopy quality control reviewers for a blinded interpretation, including assessment of image quality. Reviewers' and colposcopists' diagnoses were compared with histologic diagnoses using standard contingency table methods. Colposcopists and reviewers underdiagnosed 16.1% and 25.3% of subjects, and overdiagnosed 44.7% and 19.8% of subjects compared with histology, respectively. The sensitivity and specificity for detecting cervical intraepithelial neoplasia 2 or greater were 35.4% versus 23.2%, P <. 0001, and 89.9% versus 95.0%, P <. 0001, respectively, for colposcopists and reviewers. Colposcopy quality control by review of digitized colposcopic images in clinical trials warrants further evaluation if the accuracy can be improved.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1934-1941 |
| Number of pages | 8 |
| Journal | American Journal of Obstetrics and Gynecology |
| Volume | 191 |
| Issue number | 6 |
| DOIs | |
| State | Published - Jan 1 2004 |
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Keywords
- ATLS trial
- Cervical intraepithelial neoplasia
- Colposcopy
- Quality control
ASJC Scopus subject areas
- Obstetrics and Gynecology
Cite this
Colposcopy quality control by remote review of digitized colposcopic images. / Ferris, Daron Gale; Litaker, Mark S.
In: American Journal of Obstetrics and Gynecology, Vol. 191, No. 6, 01.01.2004, p. 1934-1941.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Colposcopy quality control by remote review of digitized colposcopic images
AU - Ferris, Daron Gale
AU - Litaker, Mark S.
PY - 2004/1/1
Y1 - 2004/1/1
N2 - This study was undertaken to estimate the accuracy of colposcopy quality control review of subjects' digitized colposcopic images during the atypical squamous cells of undetermined significance/low-grade squamous intraepithelial lesion triage study (ALTS). After colposcopic examination and the acquisition of 2 digitized cervical images, colposcopists recorded colposcopic diagnoses in a standardized computer database. The images were transferred by modem to colposcopy quality control reviewers for a blinded interpretation, including assessment of image quality. Reviewers' and colposcopists' diagnoses were compared with histologic diagnoses using standard contingency table methods. Colposcopists and reviewers underdiagnosed 16.1% and 25.3% of subjects, and overdiagnosed 44.7% and 19.8% of subjects compared with histology, respectively. The sensitivity and specificity for detecting cervical intraepithelial neoplasia 2 or greater were 35.4% versus 23.2%, P <. 0001, and 89.9% versus 95.0%, P <. 0001, respectively, for colposcopists and reviewers. Colposcopy quality control by review of digitized colposcopic images in clinical trials warrants further evaluation if the accuracy can be improved.
AB - This study was undertaken to estimate the accuracy of colposcopy quality control review of subjects' digitized colposcopic images during the atypical squamous cells of undetermined significance/low-grade squamous intraepithelial lesion triage study (ALTS). After colposcopic examination and the acquisition of 2 digitized cervical images, colposcopists recorded colposcopic diagnoses in a standardized computer database. The images were transferred by modem to colposcopy quality control reviewers for a blinded interpretation, including assessment of image quality. Reviewers' and colposcopists' diagnoses were compared with histologic diagnoses using standard contingency table methods. Colposcopists and reviewers underdiagnosed 16.1% and 25.3% of subjects, and overdiagnosed 44.7% and 19.8% of subjects compared with histology, respectively. The sensitivity and specificity for detecting cervical intraepithelial neoplasia 2 or greater were 35.4% versus 23.2%, P <. 0001, and 89.9% versus 95.0%, P <. 0001, respectively, for colposcopists and reviewers. Colposcopy quality control by review of digitized colposcopic images in clinical trials warrants further evaluation if the accuracy can be improved.
KW - ATLS trial
KW - Cervical intraepithelial neoplasia
KW - Colposcopy
KW - Quality control
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U2 - 10.1016/j.ajog.2004.06.107
DO - 10.1016/j.ajog.2004.06.107
M3 - Article
VL - 191
SP - 1934
EP - 1941
JO - American Journal of Obstetrics and Gynecology
JF - American Journal of Obstetrics and Gynecology
SN - 0002-9378
IS - 6
ER -