Comparison of conjunctival and corneal surface areas in rabbit and human

Mitchell A. Watsky, Monica M. Jablonski, Henry F. Edelhauser

Research output: Contribution to journalArticle

115 Scopus citations

Abstract

This comparative study shows the surface area ratio of conjunctiva to cornea to be two times larger in humans than in rabbits. This large heretofore unrecognized interspecies difference may affect the applicability of drug pharmacokinetic data obtained using rabbit models and should be taken into consideration in topical drug development and future comparative drug penetration studies between rabbit and man.

Original languageEnglish (US)
Pages (from-to)483-486
Number of pages4
JournalCurrent Eye Research
Volume7
Issue number5
DOIs
Publication statusPublished - Jan 1 1988
Externally publishedYes

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ASJC Scopus subject areas

  • Ophthalmology
  • Sensory Systems
  • Cellular and Molecular Neuroscience

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