Composite Tissue Adhesive as a hemostatic agent for parenchymatous trauma

D. J. Wilson, J. M. Kloss, J. J. Prior, D. H. Sierra, David J Terris

Research output: Contribution to conferencePaper

1 Citation (Scopus)

Abstract

Composite Tissue Adhesive (CTA) has been developed as a versatile hemostatic agent for the treatment of parenchymatous trauma. CTA is a fibrin-based composition formulated by adding fibrillar type I collagen to fibrinogen-Factor XIII solutions to alter the mechanical properties. CTA incorporates both collagen and fibrinogen in a formulation which is easy to administer and effective in quickly establishing hemostasis without any applied pressure. Because of its viscosity, CTA can be delivered in a controlled and traceable manner with surgical precision. A comparison of CTA with both cryoprecipitate and fibrin sealant has been conducted to evaluate their effects on hemostasis in a rat model.

Original languageEnglish (US)
Number of pages1
StatePublished - Dec 1 1996
EventProceedings of the 1996 5th World Biomaterials Congress. Part 2 (of 2) - Toronto, Can
Duration: May 29 1996Jun 2 1996

Other

OtherProceedings of the 1996 5th World Biomaterials Congress. Part 2 (of 2)
CityToronto, Can
Period5/29/966/2/96

Fingerprint

Tissue Adhesives
Hemostatics
Tissue
Composite materials
Collagen
Fibrinogen
Factor XIII
Fibrin Tissue Adhesive
Sealants
Collagen Type I
Fibrin
Rats
Viscosity
Mechanical properties
Chemical analysis

ASJC Scopus subject areas

  • Materials Science(all)

Cite this

Wilson, D. J., Kloss, J. M., Prior, J. J., Sierra, D. H., & Terris, D. J. (1996). Composite Tissue Adhesive as a hemostatic agent for parenchymatous trauma. Paper presented at Proceedings of the 1996 5th World Biomaterials Congress. Part 2 (of 2), Toronto, Can, .

Composite Tissue Adhesive as a hemostatic agent for parenchymatous trauma. / Wilson, D. J.; Kloss, J. M.; Prior, J. J.; Sierra, D. H.; Terris, David J.

1996. Paper presented at Proceedings of the 1996 5th World Biomaterials Congress. Part 2 (of 2), Toronto, Can, .

Research output: Contribution to conferencePaper

Wilson, DJ, Kloss, JM, Prior, JJ, Sierra, DH & Terris, DJ 1996, 'Composite Tissue Adhesive as a hemostatic agent for parenchymatous trauma' Paper presented at Proceedings of the 1996 5th World Biomaterials Congress. Part 2 (of 2), Toronto, Can, 5/29/96 - 6/2/96, .
Wilson DJ, Kloss JM, Prior JJ, Sierra DH, Terris DJ. Composite Tissue Adhesive as a hemostatic agent for parenchymatous trauma. 1996. Paper presented at Proceedings of the 1996 5th World Biomaterials Congress. Part 2 (of 2), Toronto, Can, .
Wilson, D. J. ; Kloss, J. M. ; Prior, J. J. ; Sierra, D. H. ; Terris, David J. / Composite Tissue Adhesive as a hemostatic agent for parenchymatous trauma. Paper presented at Proceedings of the 1996 5th World Biomaterials Congress. Part 2 (of 2), Toronto, Can, .1 p.
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