Abstract
Composite Tissue Adhesive (CTA) has been developed as a versatile hemostatic agent for the treatment of parenchymatous trauma. CTA is a fibrin-based composition formulated by adding fibrillar type I collagen to fibrinogen-Factor XIII solutions to alter the mechanical properties. CTA incorporates both collagen and fibrinogen in a formulation which is easy to administer and effective in quickly establishing hemostasis without any applied pressure. Because of its viscosity, CTA can be delivered in a controlled and traceable manner with surgical precision. A comparison of CTA with both cryoprecipitate and fibrin sealant has been conducted to evaluate their effects on hemostasis in a rat model.
Original language | English (US) |
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Pages | 17 |
Number of pages | 1 |
State | Published - 1996 |
Externally published | Yes |
Event | Proceedings of the 1996 5th World Biomaterials Congress. Part 2 (of 2) - Toronto, Can Duration: May 29 1996 → Jun 2 1996 |
Other
Other | Proceedings of the 1996 5th World Biomaterials Congress. Part 2 (of 2) |
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City | Toronto, Can |
Period | 5/29/96 → 6/2/96 |
ASJC Scopus subject areas
- General Materials Science