Comprehensive review of tissue adhesives

Lauren E. Jenkins, Loretta S Davis

Research output: Contribution to journalReview article

Abstract

BACKGROUND Cyanoacrylates, also known as tissue adhesives or skin glues, are commonly used as sealants for lacerations and incisions and have found utility in excisional and cosmetic surgeries in both outpatient and operating room settings. OBJECTIVE To review the surgical literature on the utilities, advantages, disadvantages, and special uses of cyanoacrylates applicable to dermatology. MATERIALS AND METHODS PubMed was reviewed for relevant articles related to cyanoacrylates and their use in skin closures. Articles unrelated to cutaneous closures were excluded. RESULTS Tissue adhesives polymerize to a water resistant, pliable film after application to approximated wound edges and have antibacterial properties. Adhesives slowly slough off as the wound heals, typically after 5 days. Compared with 5-0 nonabsorbable suture, adhesives provide similar tensile strength and similar patient and surgeon satisfaction. Although slightly more expensive than sutures, tissue adhesives obviate the need for wound dressings and suture removal. They do not perform as well as sutures for wounds under higher tension or in the setting of moisture and inadequate hemostasis. CONCLUSION Cyanoacrylates serve as a safe and effective suture alternative in appropriate dermatologic surgeries and procedures.

Original languageEnglish (US)
Pages (from-to)1367-1372
Number of pages6
JournalDermatologic Surgery
Volume44
Issue number11
DOIs
StatePublished - Jan 1 2018

Fingerprint

Tissue Adhesives
Cyanoacrylates
Sutures
Adhesives
Wounds and Injuries
Skin
Dermatologic Surgical Procedures
Tensile Strength
Lacerations
Plastic Surgery
Operating Rooms
Bandages
Dermatology
Hemostasis
Patient Satisfaction
PubMed
Outpatients
Water

ASJC Scopus subject areas

  • Surgery
  • Dermatology

Cite this

Comprehensive review of tissue adhesives. / Jenkins, Lauren E.; Davis, Loretta S.

In: Dermatologic Surgery, Vol. 44, No. 11, 01.01.2018, p. 1367-1372.

Research output: Contribution to journalReview article

Jenkins, Lauren E. ; Davis, Loretta S. / Comprehensive review of tissue adhesives. In: Dermatologic Surgery. 2018 ; Vol. 44, No. 11. pp. 1367-1372.
@article{bd61968aaed040c28b3645967946c7b6,
title = "Comprehensive review of tissue adhesives",
abstract = "BACKGROUND Cyanoacrylates, also known as tissue adhesives or skin glues, are commonly used as sealants for lacerations and incisions and have found utility in excisional and cosmetic surgeries in both outpatient and operating room settings. OBJECTIVE To review the surgical literature on the utilities, advantages, disadvantages, and special uses of cyanoacrylates applicable to dermatology. MATERIALS AND METHODS PubMed was reviewed for relevant articles related to cyanoacrylates and their use in skin closures. Articles unrelated to cutaneous closures were excluded. RESULTS Tissue adhesives polymerize to a water resistant, pliable film after application to approximated wound edges and have antibacterial properties. Adhesives slowly slough off as the wound heals, typically after 5 days. Compared with 5-0 nonabsorbable suture, adhesives provide similar tensile strength and similar patient and surgeon satisfaction. Although slightly more expensive than sutures, tissue adhesives obviate the need for wound dressings and suture removal. They do not perform as well as sutures for wounds under higher tension or in the setting of moisture and inadequate hemostasis. CONCLUSION Cyanoacrylates serve as a safe and effective suture alternative in appropriate dermatologic surgeries and procedures.",
author = "Jenkins, {Lauren E.} and Davis, {Loretta S}",
year = "2018",
month = "1",
day = "1",
doi = "10.1097/DSS.0000000000001576",
language = "English (US)",
volume = "44",
pages = "1367--1372",
journal = "Dermatologic Surgery",
issn = "1076-0512",
publisher = "Wiley-Blackwell",
number = "11",

}

TY - JOUR

T1 - Comprehensive review of tissue adhesives

AU - Jenkins, Lauren E.

AU - Davis, Loretta S

PY - 2018/1/1

Y1 - 2018/1/1

N2 - BACKGROUND Cyanoacrylates, also known as tissue adhesives or skin glues, are commonly used as sealants for lacerations and incisions and have found utility in excisional and cosmetic surgeries in both outpatient and operating room settings. OBJECTIVE To review the surgical literature on the utilities, advantages, disadvantages, and special uses of cyanoacrylates applicable to dermatology. MATERIALS AND METHODS PubMed was reviewed for relevant articles related to cyanoacrylates and their use in skin closures. Articles unrelated to cutaneous closures were excluded. RESULTS Tissue adhesives polymerize to a water resistant, pliable film after application to approximated wound edges and have antibacterial properties. Adhesives slowly slough off as the wound heals, typically after 5 days. Compared with 5-0 nonabsorbable suture, adhesives provide similar tensile strength and similar patient and surgeon satisfaction. Although slightly more expensive than sutures, tissue adhesives obviate the need for wound dressings and suture removal. They do not perform as well as sutures for wounds under higher tension or in the setting of moisture and inadequate hemostasis. CONCLUSION Cyanoacrylates serve as a safe and effective suture alternative in appropriate dermatologic surgeries and procedures.

AB - BACKGROUND Cyanoacrylates, also known as tissue adhesives or skin glues, are commonly used as sealants for lacerations and incisions and have found utility in excisional and cosmetic surgeries in both outpatient and operating room settings. OBJECTIVE To review the surgical literature on the utilities, advantages, disadvantages, and special uses of cyanoacrylates applicable to dermatology. MATERIALS AND METHODS PubMed was reviewed for relevant articles related to cyanoacrylates and their use in skin closures. Articles unrelated to cutaneous closures were excluded. RESULTS Tissue adhesives polymerize to a water resistant, pliable film after application to approximated wound edges and have antibacterial properties. Adhesives slowly slough off as the wound heals, typically after 5 days. Compared with 5-0 nonabsorbable suture, adhesives provide similar tensile strength and similar patient and surgeon satisfaction. Although slightly more expensive than sutures, tissue adhesives obviate the need for wound dressings and suture removal. They do not perform as well as sutures for wounds under higher tension or in the setting of moisture and inadequate hemostasis. CONCLUSION Cyanoacrylates serve as a safe and effective suture alternative in appropriate dermatologic surgeries and procedures.

UR - http://www.scopus.com/inward/record.url?scp=85055604841&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85055604841&partnerID=8YFLogxK

U2 - 10.1097/DSS.0000000000001576

DO - 10.1097/DSS.0000000000001576

M3 - Review article

VL - 44

SP - 1367

EP - 1372

JO - Dermatologic Surgery

JF - Dermatologic Surgery

SN - 1076-0512

IS - 11

ER -