Concomitant intraoperative splenic artery embolization and laparoscopic splenectomy versus laparoscopic splenectomy: comparison of treatment outcome

Joseph J. Naoum, Eric J. Silberfein, Wei Zhou, John F. Sweeney, Daniel Albo, F. Charles Brunicardi, Panagiotis Kougias, Hosam F. El Sayed, Peter H. Lin

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

Introduction: Although laparoscopic splenectomy has become the preferred treatment of choice for hematologic-related splenic disorders, intraoperative blood loss remains a common occurrence. In an effort to reduce this risk, we evaluate the potential role and clinical outcome of concomitant intraoperative splenic artery embolization and laparoscopic splenectomy. Methods: Between June 2000 and July 2005, 18 patients with hematologically related splenic disorders underwent combined intraoperative splenic artery embolization and laparoscopic splenectomy (group 1). For comparison, we studied 18 age- and gender-matched case controls undergoing same operations during the same period (group 2). Intraoperative data and clinical outcome were compared between the 2 groups. Results: Technical success was 100% in group 1. One patient in group 2 was converted to open splenectomy because of severe blood loss, resulting in a technical success rate of 95%. The mean splenic size in group 1 and group 2 was 15.5 ± 4.7 cm (range, 12-23 cm) and 15.7 ± 6.8 (range, 11-24cm), respectively (not significant [NS]). Mean operative time in group 1 and group 2 was 175 minutes and 162 minutes, respectively (NS). Significantly less intraoperative blood loss was noted in group 1 (mean, 25 mL; range, 15-63 mL) compared with group 2 (mean, 240 mL; range, 150-420 mL; P < .003). There was an even greater difference in blood loss between the 2 groups when the splenic size was greater than 18 cm (mean 35 mL in group 1 versus 350 mL in group 2, P < .001). No differences were noted in postoperative recovery, return of bowel function, or length of hospital stay between the 2 groups. Conclusions: Concomitant splenic artery embolization and laparoscopic splenic reduced operative blood loss when compared with laparoscopic splenectomy procedure alone. Splenic artery embolization is a useful intraoperative adjunctive procedure that should be considered in patients undergoing laparoscopic splenectomy for hematologic disorders who are Jehovah's Witness or with significant hypersplenism because of benefit of reduced blood loss.

Original languageEnglish (US)
Pages (from-to)713-718
Number of pages6
JournalAmerican Journal of Surgery
Volume193
Issue number6
DOIs
StatePublished - Jun 1 2007
Externally publishedYes

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Splenic Artery
Splenectomy
Length of Stay
Jehovah's Witnesses
Hypersplenism
Operative Time

Keywords

  • Complications
  • Laparoscopic splenectomy
  • Splenic artery embolization

ASJC Scopus subject areas

  • Surgery

Cite this

Concomitant intraoperative splenic artery embolization and laparoscopic splenectomy versus laparoscopic splenectomy : comparison of treatment outcome. / Naoum, Joseph J.; Silberfein, Eric J.; Zhou, Wei; Sweeney, John F.; Albo, Daniel; Brunicardi, F. Charles; Kougias, Panagiotis; El Sayed, Hosam F.; Lin, Peter H.

In: American Journal of Surgery, Vol. 193, No. 6, 01.06.2007, p. 713-718.

Research output: Contribution to journalArticle

Naoum, Joseph J. ; Silberfein, Eric J. ; Zhou, Wei ; Sweeney, John F. ; Albo, Daniel ; Brunicardi, F. Charles ; Kougias, Panagiotis ; El Sayed, Hosam F. ; Lin, Peter H. / Concomitant intraoperative splenic artery embolization and laparoscopic splenectomy versus laparoscopic splenectomy : comparison of treatment outcome. In: American Journal of Surgery. 2007 ; Vol. 193, No. 6. pp. 713-718.
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abstract = "Introduction: Although laparoscopic splenectomy has become the preferred treatment of choice for hematologic-related splenic disorders, intraoperative blood loss remains a common occurrence. In an effort to reduce this risk, we evaluate the potential role and clinical outcome of concomitant intraoperative splenic artery embolization and laparoscopic splenectomy. Methods: Between June 2000 and July 2005, 18 patients with hematologically related splenic disorders underwent combined intraoperative splenic artery embolization and laparoscopic splenectomy (group 1). For comparison, we studied 18 age- and gender-matched case controls undergoing same operations during the same period (group 2). Intraoperative data and clinical outcome were compared between the 2 groups. Results: Technical success was 100{\%} in group 1. One patient in group 2 was converted to open splenectomy because of severe blood loss, resulting in a technical success rate of 95{\%}. The mean splenic size in group 1 and group 2 was 15.5 ± 4.7 cm (range, 12-23 cm) and 15.7 ± 6.8 (range, 11-24cm), respectively (not significant [NS]). Mean operative time in group 1 and group 2 was 175 minutes and 162 minutes, respectively (NS). Significantly less intraoperative blood loss was noted in group 1 (mean, 25 mL; range, 15-63 mL) compared with group 2 (mean, 240 mL; range, 150-420 mL; P < .003). There was an even greater difference in blood loss between the 2 groups when the splenic size was greater than 18 cm (mean 35 mL in group 1 versus 350 mL in group 2, P < .001). No differences were noted in postoperative recovery, return of bowel function, or length of hospital stay between the 2 groups. Conclusions: Concomitant splenic artery embolization and laparoscopic splenic reduced operative blood loss when compared with laparoscopic splenectomy procedure alone. Splenic artery embolization is a useful intraoperative adjunctive procedure that should be considered in patients undergoing laparoscopic splenectomy for hematologic disorders who are Jehovah's Witness or with significant hypersplenism because of benefit of reduced blood loss.",
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T1 - Concomitant intraoperative splenic artery embolization and laparoscopic splenectomy versus laparoscopic splenectomy

T2 - comparison of treatment outcome

AU - Naoum, Joseph J.

AU - Silberfein, Eric J.

AU - Zhou, Wei

AU - Sweeney, John F.

AU - Albo, Daniel

AU - Brunicardi, F. Charles

AU - Kougias, Panagiotis

AU - El Sayed, Hosam F.

AU - Lin, Peter H.

PY - 2007/6/1

Y1 - 2007/6/1

N2 - Introduction: Although laparoscopic splenectomy has become the preferred treatment of choice for hematologic-related splenic disorders, intraoperative blood loss remains a common occurrence. In an effort to reduce this risk, we evaluate the potential role and clinical outcome of concomitant intraoperative splenic artery embolization and laparoscopic splenectomy. Methods: Between June 2000 and July 2005, 18 patients with hematologically related splenic disorders underwent combined intraoperative splenic artery embolization and laparoscopic splenectomy (group 1). For comparison, we studied 18 age- and gender-matched case controls undergoing same operations during the same period (group 2). Intraoperative data and clinical outcome were compared between the 2 groups. Results: Technical success was 100% in group 1. One patient in group 2 was converted to open splenectomy because of severe blood loss, resulting in a technical success rate of 95%. The mean splenic size in group 1 and group 2 was 15.5 ± 4.7 cm (range, 12-23 cm) and 15.7 ± 6.8 (range, 11-24cm), respectively (not significant [NS]). Mean operative time in group 1 and group 2 was 175 minutes and 162 minutes, respectively (NS). Significantly less intraoperative blood loss was noted in group 1 (mean, 25 mL; range, 15-63 mL) compared with group 2 (mean, 240 mL; range, 150-420 mL; P < .003). There was an even greater difference in blood loss between the 2 groups when the splenic size was greater than 18 cm (mean 35 mL in group 1 versus 350 mL in group 2, P < .001). No differences were noted in postoperative recovery, return of bowel function, or length of hospital stay between the 2 groups. Conclusions: Concomitant splenic artery embolization and laparoscopic splenic reduced operative blood loss when compared with laparoscopic splenectomy procedure alone. Splenic artery embolization is a useful intraoperative adjunctive procedure that should be considered in patients undergoing laparoscopic splenectomy for hematologic disorders who are Jehovah's Witness or with significant hypersplenism because of benefit of reduced blood loss.

AB - Introduction: Although laparoscopic splenectomy has become the preferred treatment of choice for hematologic-related splenic disorders, intraoperative blood loss remains a common occurrence. In an effort to reduce this risk, we evaluate the potential role and clinical outcome of concomitant intraoperative splenic artery embolization and laparoscopic splenectomy. Methods: Between June 2000 and July 2005, 18 patients with hematologically related splenic disorders underwent combined intraoperative splenic artery embolization and laparoscopic splenectomy (group 1). For comparison, we studied 18 age- and gender-matched case controls undergoing same operations during the same period (group 2). Intraoperative data and clinical outcome were compared between the 2 groups. Results: Technical success was 100% in group 1. One patient in group 2 was converted to open splenectomy because of severe blood loss, resulting in a technical success rate of 95%. The mean splenic size in group 1 and group 2 was 15.5 ± 4.7 cm (range, 12-23 cm) and 15.7 ± 6.8 (range, 11-24cm), respectively (not significant [NS]). Mean operative time in group 1 and group 2 was 175 minutes and 162 minutes, respectively (NS). Significantly less intraoperative blood loss was noted in group 1 (mean, 25 mL; range, 15-63 mL) compared with group 2 (mean, 240 mL; range, 150-420 mL; P < .003). There was an even greater difference in blood loss between the 2 groups when the splenic size was greater than 18 cm (mean 35 mL in group 1 versus 350 mL in group 2, P < .001). No differences were noted in postoperative recovery, return of bowel function, or length of hospital stay between the 2 groups. Conclusions: Concomitant splenic artery embolization and laparoscopic splenic reduced operative blood loss when compared with laparoscopic splenectomy procedure alone. Splenic artery embolization is a useful intraoperative adjunctive procedure that should be considered in patients undergoing laparoscopic splenectomy for hematologic disorders who are Jehovah's Witness or with significant hypersplenism because of benefit of reduced blood loss.

KW - Complications

KW - Laparoscopic splenectomy

KW - Splenic artery embolization

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