Congenital malformation continues to be a major problem for infants of diabetic mothers. Over a seven-year period, 199 insulin-requiring diabetic mothers were delivered at Vanderbilt University Medical Center. Congenital anomalies were identified in 26 (13%) newborns. There was no significant difference in the incidence of fetal anomalies between the various categories of White's classification of maternal diabetes mellitus. A review of proposed etiologies of anomalies in diabetic pregnancies is presented, and suggestions are made for the management of women with diabetes desiring to conceive.
ASJC Scopus subject areas
- Endocrinology, Diabetes and Metabolism
- Health Professions (miscellaneous)