Congenital X-linked hypogammaglobulinemia and asymptomatic hepatitis B antigen carrier state

Betty Beasley Wray, Guy B. Faguet, Henry M. Middleton, Shyuan Hsia, David T. Plaxico

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Hepatitis occurring in patients with congenital X-linked or common variable hypogammaglobulinemia has been reported to follow a usual pattern of rapid progression from acute hepatitis to either chronic active hepatitis or death. This article describes a 21-year-old black man with congenital X-linked hypogammaglobulinemia who has been known to be a hepatitis B-associated antigen carrier during a 9-year follow up period. Liver enzyme studies are normal. His immunologic studies demonstrate no impairment of cellular immunity. His brother, who has the same disease and lives in the same household, has remained negative for hepatitis B-associated antigen. This patient demonstrates that not all hypogammaglobulinemia patients invariably have a severe clinical course with hepatitis.

Original languageEnglish (US)
Pages (from-to)507-510
Number of pages4
JournalThe Journal of allergy and clinical immunology
Volume76
Issue number3
DOIs
StatePublished - Jan 1 1985
Externally publishedYes

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Hepatitis B Antigens
Carrier State
Hepatitis
Common Variable Immunodeficiency
Agammaglobulinemia
Chronic Hepatitis
Cellular Immunity
Siblings
Liver
Enzymes
X-Linked Hypogammaglobulinemia

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

Cite this

Congenital X-linked hypogammaglobulinemia and asymptomatic hepatitis B antigen carrier state. / Wray, Betty Beasley; Faguet, Guy B.; Middleton, Henry M.; Hsia, Shyuan; Plaxico, David T.

In: The Journal of allergy and clinical immunology, Vol. 76, No. 3, 01.01.1985, p. 507-510.

Research output: Contribution to journalArticle

Wray, Betty Beasley ; Faguet, Guy B. ; Middleton, Henry M. ; Hsia, Shyuan ; Plaxico, David T. / Congenital X-linked hypogammaglobulinemia and asymptomatic hepatitis B antigen carrier state. In: The Journal of allergy and clinical immunology. 1985 ; Vol. 76, No. 3. pp. 507-510.
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