Cryptic Eimeria genotypes are common across the southern but not northern hemisphere

Emily L. Clark, Sarah E. Macdonald, V. Thenmozhi, Krishnendu Kundu, Rajat Garg, Saroj Kumar, Simeon Ayoade, Kimberly M. Fornace, Isa Danladi Jatau, Abdalgader Moftah, Matthew J. Nolan, N. R. Sudhakar, A. O. Adebambo, I. A. Lawal, Ramón Álvarez Zapata, Joseph A. Awuni, H. David Chapman, Esron Karimuribo, Claire M. Mugasa, Boniface NamangalaJonathan Rushton, Xun Suo, Kumarasamy Thangaraj, Arni S R Rao, Anup K. Tewari, Partha S. Banerjee, G. Dhinakar Raj, M. Raman, Fiona M. Tomley, Damer P. Blake

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

The phylum Apicomplexa includes parasites of medical, zoonotic and veterinary significance. Understanding the global distribution and genetic diversity of these protozoa is of fundamental importance for efficient, robust and long-lasting methods of control. Eimeria spp. cause intestinal coccidiosis in all major livestock animals and are the most important parasites of domestic chickens in terms of both economic impact and animal welfare. Despite having significant negative impacts on the efficiency of food production, many fundamental questions relating to the global distribution and genetic variation of Eimeria spp. remain largely unanswered. Here, we provide the broadest map yet of Eimeria occurrence for domestic chickens, confirming that all the known species (Eimeria acervulina, Eimeria brunetti, Eimeria maxima, Eimeria mitis, Eimeria necatrix, Eimeria praecox, Eimeria tenella) are present in all six continents where chickens are found (including 21 countries). Analysis of 248 internal transcribed spacer sequences derived from 17 countries provided evidence of possible allopatric diversity for species such as E. tenella (FST values ⩽0.34) but not E. acervulina and E. mitis, and highlighted a trend towards widespread genetic variance. We found that three genetic variants described previously only in Australia and southern Africa (operational taxonomic units x, y and z) have a wide distribution across the southern, but not the northern hemisphere. While the drivers for such a polarised distribution of these operational taxonomic unit genotypes remains unclear, the occurrence of genetically variant Eimeria may pose a risk to food security and animal welfare in Europe and North America should these parasites spread to the northern hemisphere.

Original languageEnglish (US)
Pages (from-to)537-544
Number of pages8
JournalInternational Journal for Parasitology
Volume46
Issue number9
DOIs
StatePublished - Aug 1 2016

Fingerprint

Eimeria
Genotype
Eimeria tenella
Chickens
Animal Welfare
Parasites
Apicomplexa
Coccidiosis
Southern Africa
Food Supply
Zoonoses
Livestock
North America
Economics

Keywords

  • Chicken
  • Eimeria
  • Genetic diversity
  • Operational taxonomic units
  • Vaccine

ASJC Scopus subject areas

  • Parasitology
  • Infectious Diseases

Cite this

Clark, E. L., Macdonald, S. E., Thenmozhi, V., Kundu, K., Garg, R., Kumar, S., ... Blake, D. P. (2016). Cryptic Eimeria genotypes are common across the southern but not northern hemisphere. International Journal for Parasitology, 46(9), 537-544. https://doi.org/10.1016/j.ijpara.2016.05.006

Cryptic Eimeria genotypes are common across the southern but not northern hemisphere. / Clark, Emily L.; Macdonald, Sarah E.; Thenmozhi, V.; Kundu, Krishnendu; Garg, Rajat; Kumar, Saroj; Ayoade, Simeon; Fornace, Kimberly M.; Jatau, Isa Danladi; Moftah, Abdalgader; Nolan, Matthew J.; Sudhakar, N. R.; Adebambo, A. O.; Lawal, I. A.; Álvarez Zapata, Ramón; Awuni, Joseph A.; Chapman, H. David; Karimuribo, Esron; Mugasa, Claire M.; Namangala, Boniface; Rushton, Jonathan; Suo, Xun; Thangaraj, Kumarasamy; Rao, Arni S R; Tewari, Anup K.; Banerjee, Partha S.; Dhinakar Raj, G.; Raman, M.; Tomley, Fiona M.; Blake, Damer P.

In: International Journal for Parasitology, Vol. 46, No. 9, 01.08.2016, p. 537-544.

Research output: Contribution to journalArticle

Clark, EL, Macdonald, SE, Thenmozhi, V, Kundu, K, Garg, R, Kumar, S, Ayoade, S, Fornace, KM, Jatau, ID, Moftah, A, Nolan, MJ, Sudhakar, NR, Adebambo, AO, Lawal, IA, Álvarez Zapata, R, Awuni, JA, Chapman, HD, Karimuribo, E, Mugasa, CM, Namangala, B, Rushton, J, Suo, X, Thangaraj, K, Rao, ASR, Tewari, AK, Banerjee, PS, Dhinakar Raj, G, Raman, M, Tomley, FM & Blake, DP 2016, 'Cryptic Eimeria genotypes are common across the southern but not northern hemisphere', International Journal for Parasitology, vol. 46, no. 9, pp. 537-544. https://doi.org/10.1016/j.ijpara.2016.05.006
Clark, Emily L. ; Macdonald, Sarah E. ; Thenmozhi, V. ; Kundu, Krishnendu ; Garg, Rajat ; Kumar, Saroj ; Ayoade, Simeon ; Fornace, Kimberly M. ; Jatau, Isa Danladi ; Moftah, Abdalgader ; Nolan, Matthew J. ; Sudhakar, N. R. ; Adebambo, A. O. ; Lawal, I. A. ; Álvarez Zapata, Ramón ; Awuni, Joseph A. ; Chapman, H. David ; Karimuribo, Esron ; Mugasa, Claire M. ; Namangala, Boniface ; Rushton, Jonathan ; Suo, Xun ; Thangaraj, Kumarasamy ; Rao, Arni S R ; Tewari, Anup K. ; Banerjee, Partha S. ; Dhinakar Raj, G. ; Raman, M. ; Tomley, Fiona M. ; Blake, Damer P. / Cryptic Eimeria genotypes are common across the southern but not northern hemisphere. In: International Journal for Parasitology. 2016 ; Vol. 46, No. 9. pp. 537-544.
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