Abstract
PRESAGE® is a solid radiochromic dosimeter consisting of a polyurethane matrix, a triarylmethane leuco dye, and a trihalomethane initiator. Varying the composition and/or relative amounts of these constituents can affect the dose sensitivity, post-irradiation stability, and physical properties of the dosimeter. This allows customisation of PRESAGE® to meet application-specific requirements, such as low sensitivity for high dose applications, stability for remote dosimetry, optical clearing for reusability, and tissue-like elasticity for deformable dosimetry. This study evaluates five hard, non-deformable PRESAGE® formulations and six deformable PRESAGE® formulations and characterizes them for dose sensitivity and stability. Results demonstrated sensitivities in the range of 0.0029 - 0.0467 ΔOD/ (Gy·cm) for hard formulations and 0.0003 - 0.0056 ΔOD/ (Gy·cm) for deformable formulations. Exceptional stability was seen in both standard and low sensitivity non-deformable formulations, with promising applications for remote dosimetry. Deformable formulations exhibited potential for reusability with strong post-irradiation optical clearing. Tensile compression testing of the deformable formulations showed elastic response consistent with soft tissues, with further testing required for direct comparison. These results demonstrate that PRESAGE® dosimeters have the flexibility to be adapted for a wide spectrum of clinical applications.
| Original language | English (US) |
|---|---|
| Article number | 012029 |
| Journal | Journal of Physics: Conference Series |
| Volume | 444 |
| Issue number | 1 |
| DOIs | |
| State | Published - Jan 1 2013 |
| Event | 7th International Conference on 3D Radiation Dosimetry, IC3DDose 2012 - Sydney, NSW, Australia Duration: Dec 4 2012 → Dec 8 2012 |
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ASJC Scopus subject areas
- Physics and Astronomy(all)
Cite this
Customising PRESAGE® for diverse applications. / Juang, T.; Newton, J.; Niebanck, M.; Benning, R.; Adamovics, J.; Oldham, M.
In: Journal of Physics: Conference Series, Vol. 444, No. 1, 012029, 01.01.2013.Research output: Contribution to journal › Conference article
}
TY - JOUR
T1 - Customising PRESAGE® for diverse applications
AU - Juang, T.
AU - Newton, J.
AU - Niebanck, M.
AU - Benning, R.
AU - Adamovics, J.
AU - Oldham, M.
PY - 2013/1/1
Y1 - 2013/1/1
N2 - PRESAGE® is a solid radiochromic dosimeter consisting of a polyurethane matrix, a triarylmethane leuco dye, and a trihalomethane initiator. Varying the composition and/or relative amounts of these constituents can affect the dose sensitivity, post-irradiation stability, and physical properties of the dosimeter. This allows customisation of PRESAGE® to meet application-specific requirements, such as low sensitivity for high dose applications, stability for remote dosimetry, optical clearing for reusability, and tissue-like elasticity for deformable dosimetry. This study evaluates five hard, non-deformable PRESAGE® formulations and six deformable PRESAGE® formulations and characterizes them for dose sensitivity and stability. Results demonstrated sensitivities in the range of 0.0029 - 0.0467 ΔOD/ (Gy·cm) for hard formulations and 0.0003 - 0.0056 ΔOD/ (Gy·cm) for deformable formulations. Exceptional stability was seen in both standard and low sensitivity non-deformable formulations, with promising applications for remote dosimetry. Deformable formulations exhibited potential for reusability with strong post-irradiation optical clearing. Tensile compression testing of the deformable formulations showed elastic response consistent with soft tissues, with further testing required for direct comparison. These results demonstrate that PRESAGE® dosimeters have the flexibility to be adapted for a wide spectrum of clinical applications.
AB - PRESAGE® is a solid radiochromic dosimeter consisting of a polyurethane matrix, a triarylmethane leuco dye, and a trihalomethane initiator. Varying the composition and/or relative amounts of these constituents can affect the dose sensitivity, post-irradiation stability, and physical properties of the dosimeter. This allows customisation of PRESAGE® to meet application-specific requirements, such as low sensitivity for high dose applications, stability for remote dosimetry, optical clearing for reusability, and tissue-like elasticity for deformable dosimetry. This study evaluates five hard, non-deformable PRESAGE® formulations and six deformable PRESAGE® formulations and characterizes them for dose sensitivity and stability. Results demonstrated sensitivities in the range of 0.0029 - 0.0467 ΔOD/ (Gy·cm) for hard formulations and 0.0003 - 0.0056 ΔOD/ (Gy·cm) for deformable formulations. Exceptional stability was seen in both standard and low sensitivity non-deformable formulations, with promising applications for remote dosimetry. Deformable formulations exhibited potential for reusability with strong post-irradiation optical clearing. Tensile compression testing of the deformable formulations showed elastic response consistent with soft tissues, with further testing required for direct comparison. These results demonstrate that PRESAGE® dosimeters have the flexibility to be adapted for a wide spectrum of clinical applications.
UR - http://www.scopus.com/inward/record.url?scp=84883313995&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84883313995&partnerID=8YFLogxK
U2 - 10.1088/1742-6596/444/1/012029
DO - 10.1088/1742-6596/444/1/012029
M3 - Conference article
AN - SCOPUS:84883313995
VL - 444
JO - Journal of Physics: Conference Series
JF - Journal of Physics: Conference Series
SN - 1742-6588
IS - 1
M1 - 012029
ER -