Cutaneous epithelioid angiomatous nodule: A case series and proposed classification

Omar P. Sangüeza, Sarah N. Walsh, Daniel J Sheehan, Almudena Fernández Orland, Beatriz Llombart, Luis Requena

Research output: Contribution to journalArticle

43 Citations (Scopus)

Abstract

Cutaneous epithelioid angiomatous nodule is a peculiar and recently recognized vascular proliferation. Clinically, these lesions affect different areas of the body and histologically are characterized by a well-circumscribed, mainly unilobular, solid proliferation of endothelial cells with prominent epithelioid features. The cytoplasm is abundant and eosinophilic, and many of the neoplastic cells contain prominent vacuoles. Inflammatory infiltrates are variable. All the cases reported thus far have followed a benign course. We report 10 additional cases of this curious entity, including 2 which presented in an eruptive fashion and 5 that were located on the head and neck. We also discuss the histological differential diagnoses with other epithelioid proliferations and propose categorization within the spectrum of epithelioid hemangioma.

Original languageEnglish (US)
Pages (from-to)16-20
Number of pages5
JournalAmerican Journal of Dermatopathology
Volume30
Issue number1
DOIs
StatePublished - Feb 1 2008
Externally publishedYes

Fingerprint

Hemangioma
Vacuoles
Blood Vessels
Cytoplasm
Differential Diagnosis
Neck
Endothelial Cells
Head
Skin

Keywords

  • Epithelioid
  • Eruptive
  • Skin
  • Vascular neoplasms

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Dermatology

Cite this

Cutaneous epithelioid angiomatous nodule : A case series and proposed classification. / Sangüeza, Omar P.; Walsh, Sarah N.; Sheehan, Daniel J; Orland, Almudena Fernández; Llombart, Beatriz; Requena, Luis.

In: American Journal of Dermatopathology, Vol. 30, No. 1, 01.02.2008, p. 16-20.

Research output: Contribution to journalArticle

Sangüeza, Omar P. ; Walsh, Sarah N. ; Sheehan, Daniel J ; Orland, Almudena Fernández ; Llombart, Beatriz ; Requena, Luis. / Cutaneous epithelioid angiomatous nodule : A case series and proposed classification. In: American Journal of Dermatopathology. 2008 ; Vol. 30, No. 1. pp. 16-20.
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