Cyclosporine nephrotoxicity without major organ transplantation

Norris Stanley Nahman, F. G. Cosio, S. Kolkin, J. R. Mendell, H. M. Sharma

Research output: Contribution to journalArticle

13 Scopus citations

Abstract

Cyclosporine is an immunosuppressant used primarily in transplantation and more recently in the therapy of autoimmune disease. Nephrotoxicity is a well-recognized complication of cyclosporine and includes functional and anatomical damage. We report the cases of two patients given cyclosporine for immunologic diseases other than major organ transplantation. Both patients developed irreversible renal functional impairment and had renal biopsy findings consistent with chronic cyclosporine nephrotoxicity.

Original languageEnglish (US)
Pages (from-to)400-402
Number of pages3
JournalAnnals of Internal Medicine
Volume106
Issue number3
DOIs
StatePublished - Jan 1 1987
Externally publishedYes

ASJC Scopus subject areas

  • Internal Medicine

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