Cyclosporine nephrotoxicity without major organ transplantation

Norris Stanley Nahman, F. G. Cosio, S. Kolkin, J. R. Mendell, H. M. Sharma

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Cyclosporine is an immunosuppressant used primarily in transplantation and more recently in the therapy of autoimmune disease. Nephrotoxicity is a well-recognized complication of cyclosporine and includes functional and anatomical damage. We report the cases of two patients given cyclosporine for immunologic diseases other than major organ transplantation. Both patients developed irreversible renal functional impairment and had renal biopsy findings consistent with chronic cyclosporine nephrotoxicity.

Original languageEnglish (US)
Pages (from-to)400-402
Number of pages3
JournalAnnals of Internal Medicine
Volume106
Issue number3
DOIs
StatePublished - Jan 1 1987
Externally publishedYes

Fingerprint

Organ Transplantation
Cyclosporine
Kidney
Immune System Diseases
Immunosuppressive Agents
Autoimmune Diseases
Transplantation
Biopsy
Therapeutics

ASJC Scopus subject areas

  • Internal Medicine

Cite this

Cyclosporine nephrotoxicity without major organ transplantation. / Nahman, Norris Stanley; Cosio, F. G.; Kolkin, S.; Mendell, J. R.; Sharma, H. M.

In: Annals of Internal Medicine, Vol. 106, No. 3, 01.01.1987, p. 400-402.

Research output: Contribution to journalArticle

Nahman, Norris Stanley ; Cosio, F. G. ; Kolkin, S. ; Mendell, J. R. ; Sharma, H. M. / Cyclosporine nephrotoxicity without major organ transplantation. In: Annals of Internal Medicine. 1987 ; Vol. 106, No. 3. pp. 400-402.
@article{43a8e43073f14382b2c000f5507966da,
title = "Cyclosporine nephrotoxicity without major organ transplantation",
abstract = "Cyclosporine is an immunosuppressant used primarily in transplantation and more recently in the therapy of autoimmune disease. Nephrotoxicity is a well-recognized complication of cyclosporine and includes functional and anatomical damage. We report the cases of two patients given cyclosporine for immunologic diseases other than major organ transplantation. Both patients developed irreversible renal functional impairment and had renal biopsy findings consistent with chronic cyclosporine nephrotoxicity.",
author = "Nahman, {Norris Stanley} and Cosio, {F. G.} and S. Kolkin and Mendell, {J. R.} and Sharma, {H. M.}",
year = "1987",
month = "1",
day = "1",
doi = "10.7326/0003-4819-106-3-400",
language = "English (US)",
volume = "106",
pages = "400--402",
journal = "Annals of Internal Medicine",
issn = "0003-4819",
publisher = "American College of Physicians",
number = "3",

}

TY - JOUR

T1 - Cyclosporine nephrotoxicity without major organ transplantation

AU - Nahman, Norris Stanley

AU - Cosio, F. G.

AU - Kolkin, S.

AU - Mendell, J. R.

AU - Sharma, H. M.

PY - 1987/1/1

Y1 - 1987/1/1

N2 - Cyclosporine is an immunosuppressant used primarily in transplantation and more recently in the therapy of autoimmune disease. Nephrotoxicity is a well-recognized complication of cyclosporine and includes functional and anatomical damage. We report the cases of two patients given cyclosporine for immunologic diseases other than major organ transplantation. Both patients developed irreversible renal functional impairment and had renal biopsy findings consistent with chronic cyclosporine nephrotoxicity.

AB - Cyclosporine is an immunosuppressant used primarily in transplantation and more recently in the therapy of autoimmune disease. Nephrotoxicity is a well-recognized complication of cyclosporine and includes functional and anatomical damage. We report the cases of two patients given cyclosporine for immunologic diseases other than major organ transplantation. Both patients developed irreversible renal functional impairment and had renal biopsy findings consistent with chronic cyclosporine nephrotoxicity.

UR - http://www.scopus.com/inward/record.url?scp=0023121496&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0023121496&partnerID=8YFLogxK

U2 - 10.7326/0003-4819-106-3-400

DO - 10.7326/0003-4819-106-3-400

M3 - Article

VL - 106

SP - 400

EP - 402

JO - Annals of Internal Medicine

JF - Annals of Internal Medicine

SN - 0003-4819

IS - 3

ER -