Balanced chromosomal translocations in parents and Mullerian abnormalities constitute defined causes of reproductive wastage. Fifty nine couples with histories of recurrent abortion with or without fetal malformations were evaluated with cytogenetic studies and gynecography. In 44 of the couples with pure abortion histories of two or more spontaneous abortions, three (6.8%) balanced carrier parents were identified. In 11 couples with a mixed history of abortion plus fetal malformation, 3 (27.3%) had balanced translocations in one of the parents. The over all incidence of Mullerian abnormalities in the group of 59 patients was 11.9%.
ASJC Scopus subject areas
- Obstetrics and Gynecology