Cytokines in exertion-induced skeletal muscle injury

Joseph G. Cannon, Barbara A. St. Pierre

Research output: Contribution to journalReview article

125 Citations (Scopus)

Abstract

Cytokines are a diverse family of intercellular signaling proteins that influence the movement, proliferation, differentiation, metabolism and membrane processes of target cells. Synthesis and release of cytokines from leukocytes in response to microbial stimuli are well known. This review, however, will present evidence that non-infectious stimuli can induce cytokine secretion from leukocytes and other cells (including muscle cells) following myocellular injury. The biological actions and potential adaptive values of these cytokines through the course of muscle necrosis and regeneration will be described.

Original languageEnglish (US)
Pages (from-to)159-167
Number of pages9
JournalMolecular and Cellular Biochemistry
Volume179
Issue number1-2
DOIs
StatePublished - Mar 28 1998

Fingerprint

Muscle
Skeletal Muscle
Cytokines
Wounds and Injuries
Leukocytes
Metabolism
Muscle Cells
Action Potentials
Regeneration
Necrosis
Cells
Membranes
Muscles
Proteins

Keywords

  • Cytokines
  • Exercise
  • Fibroblasts
  • Leukocyte
  • Necrosis
  • Neutrophils
  • Regeneration
  • Skeletal muscle
  • Tumour necrosis factor

ASJC Scopus subject areas

  • Clinical Biochemistry
  • Molecular Biology
  • Genetics
  • Cell Biology

Cite this

Cytokines in exertion-induced skeletal muscle injury. / Cannon, Joseph G.; St. Pierre, Barbara A.

In: Molecular and Cellular Biochemistry, Vol. 179, No. 1-2, 28.03.1998, p. 159-167.

Research output: Contribution to journalReview article

Cannon, Joseph G. ; St. Pierre, Barbara A. / Cytokines in exertion-induced skeletal muscle injury. In: Molecular and Cellular Biochemistry. 1998 ; Vol. 179, No. 1-2. pp. 159-167.
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