Synovial fluid from 20 patients with rheumatoid arthritis was analyzed to detect human cytomegalovirus (CMV) genomic material using polymerase chain reaction. Of 20 samples tested, 9 were positive for CMV by either ethidium bromide staining or Southern blotting. In contrast, CMV was detected in only 2 of 18 control patients with osteoarthritis. These results suggest an etiologic relationship between CMV and rheumatoid arthritis.
|Original language||English (US)|
|Number of pages||4|
|Journal||Clinical and Experimental Rheumatology|
|State||Published - 1992|
ASJC Scopus subject areas
- Immunology and Allergy