Cytomegalovirus infection of the larynx in the acquired immunodeficiency syndrome

R. A. Marelli, Paul Williams Biddinger, J. L. Gluckman

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Abstract

CMV is the most important viral opportunist in patients with AIDS. Nearly all patients with AIDS have been exposed to CMV and the virus can be isolated from many. When CMV-related disease occurs in AIDS, it has usually involved the eye or gastrointestinal tract. In lesions in which CMV is the suspected etiology, evidence of direct pathogenicity of the virus should be obtained, usually histologically. Accurate diagnosis is essential because long-term therapy with a relatively toxic drug (ganciclovir) is indicated. We have presented a case of CMV infection of the larynx that responded, albeit slowly, to ganciclovir. Additional cases may arise as the prevalence of AIDS increases. Because of the potential for airway compromise and the tendency toward chronicity, CMV infection of the larynx should be of a significant concern both for the patient and the otolaryngologist.

Original languageEnglish (US)
Pages (from-to)296-301
Number of pages6
JournalOtolaryngology - Head and Neck Surgery
Volume106
Issue number3
StatePublished - Jan 1 1992

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ASJC Scopus subject areas

  • Surgery
  • Otorhinolaryngology

Cite this

Marelli, R. A., Biddinger, P. W., & Gluckman, J. L. (1992). Cytomegalovirus infection of the larynx in the acquired immunodeficiency syndrome. Otolaryngology - Head and Neck Surgery, 106(3), 296-301.