Daily variations in human plasma fluoride concentrations

Vanessa E S Cardoso, Gary M. Whitford, Hiroshi Aoyama, Marilia A R Buzalaf

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

This study investigated the variations in human plasma fluoride concentrations ([F]) and sought to determine the causes. Five subjects (27-33 years old) received a low-F diet during the 5 days of the study. Plasma samples and urine were collected every 3 h from 8 a.m. to 8 p.m. F, PTH, Ca and P were analyzed with the electrode, by chemiluminescence, AAS and colorimetry, respectively. A trend for the plasma [F] was found. The peak [F], 0.55 ± 0.11 μmol L-1, occurred at 11 a.m. and the lowest [F], 0.50 ± 0.06 μmol L-1 occurred between 5 and 8 p.m. Plasma [F] were positively correlated with urinary F excretion rates and with serum PTH levels, but not with the Ca or P levels. Serum PTH levels were positively correlated with urinary F excretion rates and negatively correlated with plasma Ca. The results suggest that the renal system seems to control the daily fluctuations in plasma [F].

Original languageEnglish (US)
Pages (from-to)1193-1198
Number of pages6
JournalJournal of Fluorine Chemistry
Volume129
Issue number12
DOIs
StatePublished - Dec 1 2008

Fingerprint

Plasma (human)
Fluorides
fluoride
diurnal variation
fluorides
Plasmas
plasma
excretion
serums
serum
Colorimetry
Chemiluminescence
colorimetry
diets
Nutrition
urine
chemiluminescence
Luminescence
Serum
Electrodes

Keywords

  • Biological rhythm
  • Fluoride
  • PTH
  • Plasma
  • Renal system

ASJC Scopus subject areas

  • Biochemistry
  • Inorganic Chemistry
  • Organic Chemistry
  • Physical and Theoretical Chemistry
  • Environmental Chemistry

Cite this

Daily variations in human plasma fluoride concentrations. / Cardoso, Vanessa E S; Whitford, Gary M.; Aoyama, Hiroshi; Buzalaf, Marilia A R.

In: Journal of Fluorine Chemistry, Vol. 129, No. 12, 01.12.2008, p. 1193-1198.

Research output: Contribution to journalArticle

Cardoso, Vanessa E S ; Whitford, Gary M. ; Aoyama, Hiroshi ; Buzalaf, Marilia A R. / Daily variations in human plasma fluoride concentrations. In: Journal of Fluorine Chemistry. 2008 ; Vol. 129, No. 12. pp. 1193-1198.
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