Data regarding M1 muscarinic receptor-mediated modulation of hepatic catalase activity in response to oxidative stress

Ravirajsinh N. Jadeja; Nathalie H. Urrunaga; Daniel Ahmad; Sandeep Khurana

doi:10.1016/j.dib.2015.12.025

Data regarding M1 muscarinic receptor-mediated modulation of hepatic catalase activity in response to oxidative stress

Ravirajsinh N. Jadeja, Nathalie H. Urrunaga, Daniel Ahmad, Sandeep Khurana

Gastroenterology

Research output: Contribution to journal › Article

1 Scopus citations

Abstract

We recently demonstrated the role of M1 muscarinic receptors (M1R) in modulating oxidative stress in liver and hepatocytes (Urrunaga et al., 2015) [1]. Here we provide data regarding the effect of a novel M1R agonist, VU0357017 (Lebois et al., 2010) [2], on H₂O₂-mediated hepatocyte injury, the effect of an M1R antagonist VU0255035 (Sheffler et al., 2009) [3] on catalase and super oxide dismutase (SOD) activities in H₂O₂-treated hepatocytes in vitro, and finally, the effect of M1R ablation on hepatic catalase activity in acetaminophen (APAP)-treated mice.

Original language	English (US)
Pages (from-to)	405-409
Number of pages	5
Journal	Data in Brief
Volume	6
DOIs	https://doi.org/10.1016/j.dib.2015.12.025
State	Published - Mar 1 2016

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Keywords

Catalase
Muscarinic receptors
Oxidative stress

ASJC Scopus subject areas

General

Cite this

Jadeja, R. N., Urrunaga, N. H., Ahmad, D., & Khurana, S. (2016). Data regarding M1 muscarinic receptor-mediated modulation of hepatic catalase activity in response to oxidative stress. Data in Brief, 6, 405-409. https://doi.org/10.1016/j.dib.2015.12.025

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10.1016/j.dib.2015.12.025