Abstract
Purpose: To evaluate the incidence of epithelial defects that occur with laser in situ keratomileusis (LASIK) using nonpreserved carboxymethylcellulose sodium 0.5% solution (Refresh Plus®) intraoperatively. Setting: Community-based refractive center. Methods: This retrospective study comprised 105 patients (210 eyes) who had primary bilateral LASIK by 1 of 2 surgeons between October 1 and December 1, 2000. The 114 eyes treated subsequent to November 1, 2000, received Refresh Plus intraoperatively, and the 96 eyes treated before this date did not. The incidence of epithelial defects and diffuse lamellar keratitis (DLK) in both groups was recorded. The preoperative keratometry measurements of all cases were also recorded. Results: There was a statistically significant decrease in the incidence of epithelial defects in the group that received Refresh Plus intraoperatively (P = .02). No statistically significant between-group difference in the incidence of DLK was detected. Analysis of the keratometry measurements revealed no statistically significant association between the amount or axis of astigmatism and the incidence of epithelial defects or DLK. Conclusion: The intraoperative use of nonpreserved Refresh Plus significantly decreased the rate of epithelial defects that occurred during LASIK.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1651-1654 |
| Number of pages | 4 |
| Journal | Journal of Cataract and Refractive Surgery |
| Volume | 28 |
| Issue number | 9 |
| DOIs | |
| State | Published - Sep 1 2002 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Surgery
- Ophthalmology
- Sensory Systems
Cite this
Decreased incidence of epithelial defects during laser in situ keratomileusis using intraoperative nonpreserved carboxymethylcellulose sodium 0.5% solution. / Ahee, Jason A.; Kaufman, Stephen C.; Samuel, Michael A.; Bogorad, David; Wee, Curtis.
In: Journal of Cataract and Refractive Surgery, Vol. 28, No. 9, 01.09.2002, p. 1651-1654.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Decreased incidence of epithelial defects during laser in situ keratomileusis using intraoperative nonpreserved carboxymethylcellulose sodium 0.5% solution
AU - Ahee, Jason A.
AU - Kaufman, Stephen C.
AU - Samuel, Michael A.
AU - Bogorad, David
AU - Wee, Curtis
PY - 2002/9/1
Y1 - 2002/9/1
N2 - Purpose: To evaluate the incidence of epithelial defects that occur with laser in situ keratomileusis (LASIK) using nonpreserved carboxymethylcellulose sodium 0.5% solution (Refresh Plus®) intraoperatively. Setting: Community-based refractive center. Methods: This retrospective study comprised 105 patients (210 eyes) who had primary bilateral LASIK by 1 of 2 surgeons between October 1 and December 1, 2000. The 114 eyes treated subsequent to November 1, 2000, received Refresh Plus intraoperatively, and the 96 eyes treated before this date did not. The incidence of epithelial defects and diffuse lamellar keratitis (DLK) in both groups was recorded. The preoperative keratometry measurements of all cases were also recorded. Results: There was a statistically significant decrease in the incidence of epithelial defects in the group that received Refresh Plus intraoperatively (P = .02). No statistically significant between-group difference in the incidence of DLK was detected. Analysis of the keratometry measurements revealed no statistically significant association between the amount or axis of astigmatism and the incidence of epithelial defects or DLK. Conclusion: The intraoperative use of nonpreserved Refresh Plus significantly decreased the rate of epithelial defects that occurred during LASIK.
AB - Purpose: To evaluate the incidence of epithelial defects that occur with laser in situ keratomileusis (LASIK) using nonpreserved carboxymethylcellulose sodium 0.5% solution (Refresh Plus®) intraoperatively. Setting: Community-based refractive center. Methods: This retrospective study comprised 105 patients (210 eyes) who had primary bilateral LASIK by 1 of 2 surgeons between October 1 and December 1, 2000. The 114 eyes treated subsequent to November 1, 2000, received Refresh Plus intraoperatively, and the 96 eyes treated before this date did not. The incidence of epithelial defects and diffuse lamellar keratitis (DLK) in both groups was recorded. The preoperative keratometry measurements of all cases were also recorded. Results: There was a statistically significant decrease in the incidence of epithelial defects in the group that received Refresh Plus intraoperatively (P = .02). No statistically significant between-group difference in the incidence of DLK was detected. Analysis of the keratometry measurements revealed no statistically significant association between the amount or axis of astigmatism and the incidence of epithelial defects or DLK. Conclusion: The intraoperative use of nonpreserved Refresh Plus significantly decreased the rate of epithelial defects that occurred during LASIK.
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UR - http://www.scopus.com/inward/citedby.url?scp=0036734428&partnerID=8YFLogxK
U2 - 10.1016/S0886-3350(01)01348-7
DO - 10.1016/S0886-3350(01)01348-7
M3 - Article
VL - 28
SP - 1651
EP - 1654
JO - Journal of Cataract and Refractive Surgery
JF - Journal of Cataract and Refractive Surgery
SN - 0886-3350
IS - 9
ER -