Decreased thrombogenicity of vascular prostheses following gas denucleation by hydrostatic pressure

Christopher P. Demas, Richard Vann, Edmond F Ritter, Richard S. Sepka, Bruce Klitzman, William J. Barwick

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

The high rate of thrombosis of 1.0-mm polytetrafluoroethylene (PTFE) grafts has limited their use in microvascular surgery. One possible reason for this is the blood-gas interface due to entrapped air in the interstices. The present study examines the effect on patency rates of elimination of this blood-gas interface by high pressurization. Comparing pressurized and nonpressurized grafts in the same animals showed a patency rate of 100 percent at 7 days for treated grafts, while the control (nonpressurized) grafts had all clotted by 1 hour. The implications for microvascular surgery as well as vascular surgery in general are discussed.

Original languageEnglish (US)
Pages (from-to)1042-1045
Number of pages4
JournalPlastic and Reconstructive Surgery
Volume82
Issue number6
DOIs
StatePublished - Jan 1 1988
Externally publishedYes

Fingerprint

Blood Vessel Prosthesis
Hydrostatic Pressure
Gases
Transplants
Polytetrafluoroethylene
Blood Vessels
Thrombosis
Air

ASJC Scopus subject areas

  • Surgery

Cite this

Decreased thrombogenicity of vascular prostheses following gas denucleation by hydrostatic pressure. / Demas, Christopher P.; Vann, Richard; Ritter, Edmond F; Sepka, Richard S.; Klitzman, Bruce; Barwick, William J.

In: Plastic and Reconstructive Surgery, Vol. 82, No. 6, 01.01.1988, p. 1042-1045.

Research output: Contribution to journalArticle

Demas, Christopher P. ; Vann, Richard ; Ritter, Edmond F ; Sepka, Richard S. ; Klitzman, Bruce ; Barwick, William J. / Decreased thrombogenicity of vascular prostheses following gas denucleation by hydrostatic pressure. In: Plastic and Reconstructive Surgery. 1988 ; Vol. 82, No. 6. pp. 1042-1045.
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