Deficiency of indoleamine 2,3-dioxygenase enhances commensal-induced antibody responses and protects against Citrobacter rodentium-induced colitis

Agriculture & Biology

• Citrobacter rodentium 100%
• indoleamine 2,3-dioxygenase 92%
• colitis 76%
• antibody formation 53%
• immunoglobulin A 49%
• Citrobacter 36%
• intestinal secretions 26%
• kynurenine 26%
• intestinal microorganisms 18%
• immunity 15%
• mice 15%
• picolinic acid 15%
• mouth 14%
• antibodies 11%
• dendritic cells 11%
• pathogens 10%
• young adults 9%
• splenocytes 9%
• lymph nodes 9%
• B-lymphocytes 8%
• lipopolysaccharides 8%
• tryptophan 8%
• apoptosis 8%
• small intestine 8%
• macrophages 8%
• weaning 7%
• animals 7%
• lymphocytes 7%
• antibiotics 6%
• metabolites 6%
• mutants 5%
• infection 4%

Medicine & Life Sciences

• Citrobacter rodentium 87%
• Indoleamine-Pyrrole 2,3,-Dioxygenase 73%
• Colitis 56%
• Antibody Formation 48%
• Citrobacter 39%
• Intestinal Secretions 25%
• Immunoglobulin A 25%
• Kynurenine 24%
• Gastrointestinal Microbiome 17%
• Immunity 14%
• picolinic acid 14%
• Immunoglobulin G 13%
• Secretory Immunoglobulin A 11%
• Antibodies 10%
• Weaning 9%
• Tryptophan 9%
• Animals 9%
• Small Intestine 8%
• Serum 8%
• Dendritic Cells 8%
• Immunoglobulin M 8%
• Lipopolysaccharides 7%
• Young Adult 7%
• B-Lymphocytes 6%
• Lymph Nodes 6%
• Macrophages 6%
• Lymphocytes 6%
• Anti-Bacterial Agents 5%
• Apoptosis 5%
• Infections 4%
• In Vitro Techniques 3%