Degree of facial and body terminal hair growth in unselected black and white women: Toward a populational definition of hirsutism

Catherine Marin DeUgarte, K. S. Woods, Alfred A. Bartolucci, Ricardo Azziz

Research output: Contribution to journalArticle

128 Citations (Scopus)

Abstract

Context: Hirsutism (i.e. facial and body terminal hair growth in a male-like pattern in women) is the principal clinical sign of hyperandrogenism, although its definition remains unclear. Objective: The purposes of the present study were to define 1) the degree of facial and body terminal hair, as assessed by the modified Ferriman-Gallwey (mFG) score, in unselected women from the general population; 2) the effect of race (Black and White) on the same; and 3) the normative cutoff values. Design and Setting: We conducted a prospective observational study at a tertiary academic medical center. Patients/ Participants: Participants included 633 unselected White (n = 283) and Black (n = 350) women presenting for a preemployment physical exam. Interventions: Interventions included history and physical examination. Main Outcome Measures: Terminal body hair growth was assessed using the mFG scoring system; nine body areas were scored from 0-4 for terminal hair growth distribution. Results: The mFG scores were not normally distributed; although cluster analysis failed to identify a natural cutoff value or clustering of the population, principal component and univariate analyses denoted two nearly distinct clusters that occurred above and below an mFG value of 2, with the bulk of the scores below. Overall, an mFG score of at least 3 was observed in 22.1% of all subjects (i.e. the upper quartile); of these subjects, 69.3% complained of being hirsute, compared with 15.8% of women with an mFG score below this value, and similar to the proportion of women with an mFG score of at least 8 who considered themselves to be hirsute (70.0%). Overall, there were no significant differences between Black and White women. Conclusions: Our data indicate that the prevalence and degree of facial and body terminal hair growth, as assessed by the mFG score, is similar in Black and White women and that an mFG of at least 3 signals the population of women whose hair growth falls out of the norm.

Original languageEnglish (US)
Pages (from-to)1345-1350
Number of pages6
JournalJournal of Clinical Endocrinology and Metabolism
Volume91
Issue number4
DOIs
StatePublished - Apr 1 2006

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Hirsutism
Hair
Growth
Cluster Analysis
Cluster analysis
Population
Hyperandrogenism
hydroquinone
Principal Component Analysis
Physical Examination
Observational Studies
History
Outcome Assessment (Health Care)
Prospective Studies

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Biochemistry
  • Endocrinology
  • Clinical Biochemistry
  • Biochemistry, medical

Cite this

Degree of facial and body terminal hair growth in unselected black and white women : Toward a populational definition of hirsutism. / DeUgarte, Catherine Marin; Woods, K. S.; Bartolucci, Alfred A.; Azziz, Ricardo.

In: Journal of Clinical Endocrinology and Metabolism, Vol. 91, No. 4, 01.04.2006, p. 1345-1350.

Research output: Contribution to journalArticle

DeUgarte, Catherine Marin ; Woods, K. S. ; Bartolucci, Alfred A. ; Azziz, Ricardo. / Degree of facial and body terminal hair growth in unselected black and white women : Toward a populational definition of hirsutism. In: Journal of Clinical Endocrinology and Metabolism. 2006 ; Vol. 91, No. 4. pp. 1345-1350.
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abstract = "Context: Hirsutism (i.e. facial and body terminal hair growth in a male-like pattern in women) is the principal clinical sign of hyperandrogenism, although its definition remains unclear. Objective: The purposes of the present study were to define 1) the degree of facial and body terminal hair, as assessed by the modified Ferriman-Gallwey (mFG) score, in unselected women from the general population; 2) the effect of race (Black and White) on the same; and 3) the normative cutoff values. Design and Setting: We conducted a prospective observational study at a tertiary academic medical center. Patients/ Participants: Participants included 633 unselected White (n = 283) and Black (n = 350) women presenting for a preemployment physical exam. Interventions: Interventions included history and physical examination. Main Outcome Measures: Terminal body hair growth was assessed using the mFG scoring system; nine body areas were scored from 0-4 for terminal hair growth distribution. Results: The mFG scores were not normally distributed; although cluster analysis failed to identify a natural cutoff value or clustering of the population, principal component and univariate analyses denoted two nearly distinct clusters that occurred above and below an mFG value of 2, with the bulk of the scores below. Overall, an mFG score of at least 3 was observed in 22.1{\%} of all subjects (i.e. the upper quartile); of these subjects, 69.3{\%} complained of being hirsute, compared with 15.8{\%} of women with an mFG score below this value, and similar to the proportion of women with an mFG score of at least 8 who considered themselves to be hirsute (70.0{\%}). Overall, there were no significant differences between Black and White women. Conclusions: Our data indicate that the prevalence and degree of facial and body terminal hair growth, as assessed by the mFG score, is similar in Black and White women and that an mFG of at least 3 signals the population of women whose hair growth falls out of the norm.",
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