Demographic and clinical factors associated with suicide in gastric cancer in the United States

Mallory B. Bowden, Nathaniel J. Walsh, Andrew J. Jones, Asif M. Talukder, Andrew G. Lawson, Edward James Kruse

Research output: Contribution to journalReview article

3 Citations (Scopus)

Abstract

While increased suicidal tendencies among cancer patients have been well documented, there has been no specific examination of suicide and gastric cancer. The purpose of this study is to characterize suicide incidence among patients diagnosed with gastric cancer from 1973 to 2013 and identify variables associated with higher suicide rates. Patients with gastric cancer were identified in the Surveillance, Epidemiology, and End Results (SEER) database of the National Cancer Institute. The study included clinical and demographic data from 1973 to 2013. Standardized mortality ratios (SMRs) and 95% confidence intervals (95% CIs) were calculated. Comparisons with the general US population were based on mortality data collected by the Centers for Disease Control and Prevention's National Center for Injury Prevention and Control using the Web-based Injury Statistics Query and Reporting System. Multivariable logistic regression models generated odds ratios (ORs) to assess factors associated with increased suicide in gastric malignancy. There were 210 suicides for patients with gastric cancer (SMR, 3.21; 95% CI: 2.80-3.67). Female gender (SMR 8.54), White race (SMR 4.08), age ≤39 years (SMR 3.06), and age 70-79 years (SMR 2.90), were found to be significant for an increased incidence of suicide compared with the general population. There was not a statistically significant relationship between suicide and marital status, income, mode of radiation therapy, and the role of surgical intervention. Approximately 77% of deaths by suicide occurred within the first year following diagnosis. Female gender, White race, age ≤39 years, and age 70-79 years are factors associated with increased risk of suicide in patients with gastric cancer. These results, coupled with further studies and analyses, will be used to formulate a comprehensive suicide risk factor scoring system for screening all cancer patients.

Original languageEnglish (US)
Pages (from-to)897-901
Number of pages5
JournalJournal of Gastrointestinal Oncology
Volume8
Issue number5
DOIs
StatePublished - Oct 1 2017

Fingerprint

Suicide
Stomach Neoplasms
Demography
Mortality
Logistic Models
Confidence Intervals
National Cancer Institute (U.S.)
Incidence
Wounds and Injuries
Marital Status
Centers for Disease Control and Prevention (U.S.)
Early Detection of Cancer
Population
Neoplasms
Stomach
Epidemiology
Radiotherapy
Odds Ratio
Databases

Keywords

  • And End Results (SEER) Database
  • Epidemiology
  • Gastric cancer
  • Mortality
  • Standardized mortality ratio (SMR)
  • Suicide
  • Surveillance

ASJC Scopus subject areas

  • Oncology
  • Gastroenterology

Cite this

Demographic and clinical factors associated with suicide in gastric cancer in the United States. / Bowden, Mallory B.; Walsh, Nathaniel J.; Jones, Andrew J.; Talukder, Asif M.; Lawson, Andrew G.; Kruse, Edward James.

In: Journal of Gastrointestinal Oncology, Vol. 8, No. 5, 01.10.2017, p. 897-901.

Research output: Contribution to journalReview article

Bowden, Mallory B. ; Walsh, Nathaniel J. ; Jones, Andrew J. ; Talukder, Asif M. ; Lawson, Andrew G. ; Kruse, Edward James. / Demographic and clinical factors associated with suicide in gastric cancer in the United States. In: Journal of Gastrointestinal Oncology. 2017 ; Vol. 8, No. 5. pp. 897-901.
@article{e201f0e8351e41c4a691021027f581e8,
title = "Demographic and clinical factors associated with suicide in gastric cancer in the United States",
abstract = "While increased suicidal tendencies among cancer patients have been well documented, there has been no specific examination of suicide and gastric cancer. The purpose of this study is to characterize suicide incidence among patients diagnosed with gastric cancer from 1973 to 2013 and identify variables associated with higher suicide rates. Patients with gastric cancer were identified in the Surveillance, Epidemiology, and End Results (SEER) database of the National Cancer Institute. The study included clinical and demographic data from 1973 to 2013. Standardized mortality ratios (SMRs) and 95{\%} confidence intervals (95{\%} CIs) were calculated. Comparisons with the general US population were based on mortality data collected by the Centers for Disease Control and Prevention's National Center for Injury Prevention and Control using the Web-based Injury Statistics Query and Reporting System. Multivariable logistic regression models generated odds ratios (ORs) to assess factors associated with increased suicide in gastric malignancy. There were 210 suicides for patients with gastric cancer (SMR, 3.21; 95{\%} CI: 2.80-3.67). Female gender (SMR 8.54), White race (SMR 4.08), age ≤39 years (SMR 3.06), and age 70-79 years (SMR 2.90), were found to be significant for an increased incidence of suicide compared with the general population. There was not a statistically significant relationship between suicide and marital status, income, mode of radiation therapy, and the role of surgical intervention. Approximately 77{\%} of deaths by suicide occurred within the first year following diagnosis. Female gender, White race, age ≤39 years, and age 70-79 years are factors associated with increased risk of suicide in patients with gastric cancer. These results, coupled with further studies and analyses, will be used to formulate a comprehensive suicide risk factor scoring system for screening all cancer patients.",
keywords = "And End Results (SEER) Database, Epidemiology, Gastric cancer, Mortality, Standardized mortality ratio (SMR), Suicide, Surveillance",
author = "Bowden, {Mallory B.} and Walsh, {Nathaniel J.} and Jones, {Andrew J.} and Talukder, {Asif M.} and Lawson, {Andrew G.} and Kruse, {Edward James}",
year = "2017",
month = "10",
day = "1",
doi = "10.21037/jgo.2017.08.02",
language = "English (US)",
volume = "8",
pages = "897--901",
journal = "Journal of Gastrointestinal Oncology",
issn = "2078-6891",
publisher = "Pioneer Bioscience Publishing Company (PBPC)",
number = "5",

}

TY - JOUR

T1 - Demographic and clinical factors associated with suicide in gastric cancer in the United States

AU - Bowden, Mallory B.

AU - Walsh, Nathaniel J.

AU - Jones, Andrew J.

AU - Talukder, Asif M.

AU - Lawson, Andrew G.

AU - Kruse, Edward James

PY - 2017/10/1

Y1 - 2017/10/1

N2 - While increased suicidal tendencies among cancer patients have been well documented, there has been no specific examination of suicide and gastric cancer. The purpose of this study is to characterize suicide incidence among patients diagnosed with gastric cancer from 1973 to 2013 and identify variables associated with higher suicide rates. Patients with gastric cancer were identified in the Surveillance, Epidemiology, and End Results (SEER) database of the National Cancer Institute. The study included clinical and demographic data from 1973 to 2013. Standardized mortality ratios (SMRs) and 95% confidence intervals (95% CIs) were calculated. Comparisons with the general US population were based on mortality data collected by the Centers for Disease Control and Prevention's National Center for Injury Prevention and Control using the Web-based Injury Statistics Query and Reporting System. Multivariable logistic regression models generated odds ratios (ORs) to assess factors associated with increased suicide in gastric malignancy. There were 210 suicides for patients with gastric cancer (SMR, 3.21; 95% CI: 2.80-3.67). Female gender (SMR 8.54), White race (SMR 4.08), age ≤39 years (SMR 3.06), and age 70-79 years (SMR 2.90), were found to be significant for an increased incidence of suicide compared with the general population. There was not a statistically significant relationship between suicide and marital status, income, mode of radiation therapy, and the role of surgical intervention. Approximately 77% of deaths by suicide occurred within the first year following diagnosis. Female gender, White race, age ≤39 years, and age 70-79 years are factors associated with increased risk of suicide in patients with gastric cancer. These results, coupled with further studies and analyses, will be used to formulate a comprehensive suicide risk factor scoring system for screening all cancer patients.

AB - While increased suicidal tendencies among cancer patients have been well documented, there has been no specific examination of suicide and gastric cancer. The purpose of this study is to characterize suicide incidence among patients diagnosed with gastric cancer from 1973 to 2013 and identify variables associated with higher suicide rates. Patients with gastric cancer were identified in the Surveillance, Epidemiology, and End Results (SEER) database of the National Cancer Institute. The study included clinical and demographic data from 1973 to 2013. Standardized mortality ratios (SMRs) and 95% confidence intervals (95% CIs) were calculated. Comparisons with the general US population were based on mortality data collected by the Centers for Disease Control and Prevention's National Center for Injury Prevention and Control using the Web-based Injury Statistics Query and Reporting System. Multivariable logistic regression models generated odds ratios (ORs) to assess factors associated with increased suicide in gastric malignancy. There were 210 suicides for patients with gastric cancer (SMR, 3.21; 95% CI: 2.80-3.67). Female gender (SMR 8.54), White race (SMR 4.08), age ≤39 years (SMR 3.06), and age 70-79 years (SMR 2.90), were found to be significant for an increased incidence of suicide compared with the general population. There was not a statistically significant relationship between suicide and marital status, income, mode of radiation therapy, and the role of surgical intervention. Approximately 77% of deaths by suicide occurred within the first year following diagnosis. Female gender, White race, age ≤39 years, and age 70-79 years are factors associated with increased risk of suicide in patients with gastric cancer. These results, coupled with further studies and analyses, will be used to formulate a comprehensive suicide risk factor scoring system for screening all cancer patients.

KW - And End Results (SEER) Database

KW - Epidemiology

KW - Gastric cancer

KW - Mortality

KW - Standardized mortality ratio (SMR)

KW - Suicide

KW - Surveillance

UR - http://www.scopus.com/inward/record.url?scp=85031662877&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85031662877&partnerID=8YFLogxK

U2 - 10.21037/jgo.2017.08.02

DO - 10.21037/jgo.2017.08.02

M3 - Review article

VL - 8

SP - 897

EP - 901

JO - Journal of Gastrointestinal Oncology

JF - Journal of Gastrointestinal Oncology

SN - 2078-6891

IS - 5

ER -