Dendrimer-based RNA interference delivery for cancer therapy

Leyuan Xu, W. Andrew Yeudall, Hu Yang

Research output: Chapter in Book/Report/Conference proceedingConference contribution

8 Scopus citations

Abstract

RNA interference (RNAi) has emerged as a promising tool for cancer treatment. A strenuous ongoing effort for translation of RNAi into clinically acceptable therapy is the development of vectors for efficient and targeted RNAi delivery. In this chapter, we review RNAi-based cancer treatment and the utility of dendrimers in RNAi delivery.

Original languageEnglish (US)
Title of host publicationTailored Polymer Architectures for Pharmaceutical and Biomedical Applications
PublisherAmerican Chemical Society
Pages197-213
Number of pages17
ISBN (Print)9780841227989
DOIs
StatePublished - Jul 8 2013
Externally publishedYes

Publication series

NameACS Symposium Series
Volume1135
ISSN (Print)0097-6156
ISSN (Electronic)1947-5918

ASJC Scopus subject areas

  • Chemistry(all)
  • Chemical Engineering(all)

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  • Cite this

    Xu, L., Andrew Yeudall, W., & Yang, H. (2013). Dendrimer-based RNA interference delivery for cancer therapy. In Tailored Polymer Architectures for Pharmaceutical and Biomedical Applications (pp. 197-213). (ACS Symposium Series; Vol. 1135). American Chemical Society. https://doi.org/10.1021/bk-2013-1135.ch012