Dendritic cells

A specialized complex system of antigen presenting cells

Levi H Makala, Hideyuki Nagasawa

Research output: Contribution to journalReview article

16 Citations (Scopus)

Abstract

The dendritic cell (DC) network is a specialized system for presenting antigen to naive or quiescent T cells, and consequently plays a central role in the induction of T cell and B cell immunity in vivo. Despite considerable achievements in the last ten years, in our understanding of how DC induce and regulate immune responses, much remains to be learned about this complex system of cells. The history and current status of DC termed "directors of the immune system orchestra" is reviewed. The present understanding of DC cell biology, function and use, taking into account their complexity is discussed.

Original languageEnglish (US)
Pages (from-to)181-193
Number of pages13
JournalJournal of Veterinary Medical Science
Volume64
Issue number3
DOIs
StatePublished - Mar 1 2002

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antigen-presenting cells
Antigen-Presenting Cells
dendritic cells
Dendritic Cells
T-lymphocytes
T-Lymphocytes
cell biology
B-lymphocytes
Cell Biology
immune system
Immune System
Immunity
B-Lymphocytes
immunity
History
immune response
antigens
Antigens
history
Dendritic cells

Keywords

  • Classification
  • Dendritic cell
  • Feature
  • Ontogeny

ASJC Scopus subject areas

  • veterinary(all)

Cite this

Dendritic cells : A specialized complex system of antigen presenting cells. / Makala, Levi H; Nagasawa, Hideyuki.

In: Journal of Veterinary Medical Science, Vol. 64, No. 3, 01.03.2002, p. 181-193.

Research output: Contribution to journalReview article

Makala, Levi H ; Nagasawa, Hideyuki. / Dendritic cells : A specialized complex system of antigen presenting cells. In: Journal of Veterinary Medical Science. 2002 ; Vol. 64, No. 3. pp. 181-193.
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