Dentin sialophosphoprotein (DSPP) gene-silencing inhibits key tumorigenic activities in human oral cancer cell line, OSC2

Agriculture & Biology

• mouth neoplasms 100%
• gene silencing 63%
• neoplasm cells 53%
• teeth 51%
• cell lines 43%
• stromelysin 1 26%
• small interfering RNA 24%
• gelatinase B 23%
• gelatinase A 22%
• mouth 12%
• carcinogenesis 11%
• RNA interference 10%
• apoptosis 9%
• cells 8%
• Biological Sciences 7%
• squamous cell carcinoma 7%
• cell cycle checkpoints 6%
• cisplatin 6%
• puromycin 6%
• integrins 6%
• least squares 5%
• flow cytometry 5%
• cell structures 5%
• cell viability 4%
• aggression 4%
• ligands 4%
• cell cycle 4%
• Western blotting 4%
• glycoproteins 4%
• reverse transcriptase polymerase chain reaction 4%
• neoplasms 4%
• plasmids 4%
• viability 4%
• gene expression 3%
• methodology 1%

Medicine & Life Sciences

• dentin sialophosphoprotein 90%
• Mouth Neoplasms 64%
• Gene Silencing 62%
• Human Activities 58%
• Matrix Metalloproteinases 51%
• Cell Line 34%
• Small Interfering RNA 17%
• RNA Interference 10%
• Vascular Endothelial Growth Factor A 9%
• Carcinogenesis 8%
• Puromycin 7%
• G1 Phase Cell Cycle Checkpoints 6%
• Apoptosis 6%
• Least-Squares Analysis 5%
• Integrins 5%
• Cisplatin 4%
• Glycoproteins 4%
• Squamous Cell Carcinoma 4%
• Plasmids 4%
• Cell Cycle 4%
• Flow Cytometry 4%
• Cell Survival 4%
• Up-Regulation 3%
• Ligands 3%
• Down-Regulation 3%
• Western Blotting 3%
• Neoplasms 3%
• Gene Expression 3%
• Polymerase Chain Reaction 3%
• Messenger RNA 3%

Chemical Compounds

• Tumorigenic 87%
• Small Interfering RNA 22%
• Puromycin 7%
• Cytometry 5%
• Cell Viability 5%
• Glycoprotein 4%
• Flow 3%
• Ligand 2%