Abstract
Several 3-chloro-1-[(2-phenylquinazolin-4-yl) oxy acetamidyl]-4- (substituted aryl)-2-azetidinones and 2-(substituted aryl)-3-[(2- phenylquinazolin-4-yl) oxy acetamidyl]-4-thiazolidinones were prepared by condensing 2-phenyl-4-(substituted benzylidine hydrazido methyloxy) quinazolines with chloroacetyl chloride and mercapto acetic acid respectively. These structures were established by IR and 1HNMR spectral data. These synthesized compounds were tested for their sedative, antibacterial and antifungal activities.
Original language | English (US) |
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Pages (from-to) | 84-89 |
Number of pages | 6 |
Journal | Indian Drugs |
Volume | 45 |
Issue number | 2 |
State | Published - Feb 2008 |
Externally published | Yes |
Keywords
- Antibacterial agents
- Antifungal agents
- Azitidinone
- Quinazoline
- Sedative activity
- Thiazolidinone
ASJC Scopus subject areas
- Pharmacology
- Pharmaceutical Science
- Drug Discovery