Detection of lactobacilli in monthly mail-in stool samples from 3-18 months old infants at genetic risk for type 1 diabetes

F. Salami; M. Abels; H. Hyöty; F. Vaziri-Sani; C. A. Aronsson; K. Vehik; A. Delli; W. A. Hagopian; M. Rewers; A. G. Ziegler; O. Simell; B. Akolkar; J. Krischer; J. She; Å Leramark

Detection of lactobacilli in monthly mail-in stool samples from 3-18 months old infants at genetic risk for type 1 diabetes

F. Salami, M. Abels, H. Hyöty, F. Vaziri-Sani, C. A. Aronsson, K. Vehik, A. Delli, W. A. Hagopian, M. Rewers, A. G. Ziegler, O. Simell, B. Akolkar, J. Krischer, J. She, Å Leramark

Obstetrics and Gynecology

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

The feasibility to detect lactobacilli in mail-in infant stools collected monthly from 3-18 months old children was investigated. The aim was to determine total lactobacilli and Lactobacillus plantarum (L. plantarum) content (ng/g feces) in 50 infants each from Colorado (648 samples), Finland (624 samples) and Sweden (685 samples) who participated in the TEDDY (The Environmental Determinants of Diabetes in the Young) study. Total lactobacilli content varied markedly between 5 and 16,800 ng/g feces in the three clinical sites within and between individuals especially in infants. L.plantarum also varied markedly intra- and interindividually from <0.5-736 ng/g feces. A higher variability of total lactobacilli was found before 10 months of age than after in the three different clinical sites. Sweden had the lowest total lactobacilli content compared to Colorado and Finland while the L.plantarum content was higher in Sweden. Mailin stool samples from infants should prove useful in analyzing probiotics in childhood.

Original language	English (US)
Pages (from-to)	135-144
Number of pages	10
Journal	International Journal of Probiotics and Prebiotics
Volume	7
Issue number	3-4
State	Published - 2012

Keywords

Autoimmune diabetes
Celiac disease
Infants
Microflora
Probiotics

ASJC Scopus subject areas

Food Animals
Applied Microbiology and Biotechnology
Nutrition and Dietetics
Public Health, Environmental and Occupational Health

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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Salami, F., Abels, M., Hyöty, H., Vaziri-Sani, F., Aronsson, C. A., Vehik, K., Delli, A., Hagopian, W. A., Rewers, M., Ziegler, A. G., Simell, O., Akolkar, B., Krischer, J., She, J., & Leramark, Å. (2012). Detection of lactobacilli in monthly mail-in stool samples from 3-18 months old infants at genetic risk for type 1 diabetes. International Journal of Probiotics and Prebiotics, 7(3-4), 135-144.

Salami, F, Abels, M, Hyöty, H, Vaziri-Sani, F, Aronsson, CA, Vehik, K, Delli, A, Hagopian, WA, Rewers, M, Ziegler, AG, Simell, O, Akolkar, B, Krischer, J, She, J & Leramark, Å 2012, 'Detection of lactobacilli in monthly mail-in stool samples from 3-18 months old infants at genetic risk for type 1 diabetes', International Journal of Probiotics and Prebiotics, vol. 7, no. 3-4, pp. 135-144.

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abstract = "The feasibility to detect lactobacilli in mail-in infant stools collected monthly from 3-18 months old children was investigated. The aim was to determine total lactobacilli and Lactobacillus plantarum (L. plantarum) content (ng/g feces) in 50 infants each from Colorado (648 samples), Finland (624 samples) and Sweden (685 samples) who participated in the TEDDY (The Environmental Determinants of Diabetes in the Young) study. Total lactobacilli content varied markedly between 5 and 16,800 ng/g feces in the three clinical sites within and between individuals especially in infants. L.plantarum also varied markedly intra- and interindividually from <0.5-736 ng/g feces. A higher variability of total lactobacilli was found before 10 months of age than after in the three different clinical sites. Sweden had the lowest total lactobacilli content compared to Colorado and Finland while the L.plantarum content was higher in Sweden. Mailin stool samples from infants should prove useful in analyzing probiotics in childhood.",

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Detection of lactobacilli in monthly mail-in stool samples from 3-18 months old infants at genetic risk for type 1 diabetes

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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