Detection of lactobacilli in monthly mail-in stool samples from 3-18 months old infants at genetic risk for type 1 diabetes

F. Salami, M. Abels, H. Hyöty, F. Vaziri-Sani, C. A. Aronsson, K. Vehik, A. Delli, W. A. Hagopian, M. Rewers, A. G. Ziegler, O. Simell, B. Akolkar, J. Krischer, Jin-Xiong She, Å Leramark

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

The feasibility to detect lactobacilli in mail-in infant stools collected monthly from 3-18 months old children was investigated. The aim was to determine total lactobacilli and Lactobacillus plantarum (L. plantarum) content (ng/g feces) in 50 infants each from Colorado (648 samples), Finland (624 samples) and Sweden (685 samples) who participated in the TEDDY (The Environmental Determinants of Diabetes in the Young) study. Total lactobacilli content varied markedly between 5 and 16,800 ng/g feces in the three clinical sites within and between individuals especially in infants. L.plantarum also varied markedly intra- and interindividually from <0.5-736 ng/g feces. A higher variability of total lactobacilli was found before 10 months of age than after in the three different clinical sites. Sweden had the lowest total lactobacilli content compared to Colorado and Finland while the L.plantarum content was higher in Sweden. Mailin stool samples from infants should prove useful in analyzing probiotics in childhood.

Original languageEnglish (US)
Pages (from-to)135-144
Number of pages10
JournalInternational Journal of Probiotics and Prebiotics
Volume7
Issue number3-4
StatePublished - Dec 1 2012

Fingerprint

insulin-dependent diabetes mellitus
Postal Service
Lactobacillus
Type 1 Diabetes Mellitus
Sweden
Feces
feces
Finland
sampling
Lactobacillus plantarum
Probiotics
childhood
probiotics
diabetes

Keywords

  • Autoimmune diabetes
  • Celiac disease
  • Infants
  • Microflora
  • Probiotics

ASJC Scopus subject areas

  • Food Animals
  • Applied Microbiology and Biotechnology
  • Nutrition and Dietetics
  • Public Health, Environmental and Occupational Health

Cite this

Salami, F., Abels, M., Hyöty, H., Vaziri-Sani, F., Aronsson, C. A., Vehik, K., ... Leramark, Å. (2012). Detection of lactobacilli in monthly mail-in stool samples from 3-18 months old infants at genetic risk for type 1 diabetes. International Journal of Probiotics and Prebiotics, 7(3-4), 135-144.

Detection of lactobacilli in monthly mail-in stool samples from 3-18 months old infants at genetic risk for type 1 diabetes. / Salami, F.; Abels, M.; Hyöty, H.; Vaziri-Sani, F.; Aronsson, C. A.; Vehik, K.; Delli, A.; Hagopian, W. A.; Rewers, M.; Ziegler, A. G.; Simell, O.; Akolkar, B.; Krischer, J.; She, Jin-Xiong; Leramark, Å.

In: International Journal of Probiotics and Prebiotics, Vol. 7, No. 3-4, 01.12.2012, p. 135-144.

Research output: Contribution to journalArticle

Salami, F, Abels, M, Hyöty, H, Vaziri-Sani, F, Aronsson, CA, Vehik, K, Delli, A, Hagopian, WA, Rewers, M, Ziegler, AG, Simell, O, Akolkar, B, Krischer, J, She, J-X & Leramark, Å 2012, 'Detection of lactobacilli in monthly mail-in stool samples from 3-18 months old infants at genetic risk for type 1 diabetes', International Journal of Probiotics and Prebiotics, vol. 7, no. 3-4, pp. 135-144.
Salami, F. ; Abels, M. ; Hyöty, H. ; Vaziri-Sani, F. ; Aronsson, C. A. ; Vehik, K. ; Delli, A. ; Hagopian, W. A. ; Rewers, M. ; Ziegler, A. G. ; Simell, O. ; Akolkar, B. ; Krischer, J. ; She, Jin-Xiong ; Leramark, Å. / Detection of lactobacilli in monthly mail-in stool samples from 3-18 months old infants at genetic risk for type 1 diabetes. In: International Journal of Probiotics and Prebiotics. 2012 ; Vol. 7, No. 3-4. pp. 135-144.
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