Detection of lung lesions and lymph nodes with 201 t1 spet

Ali Syed Arbab, K. Toyama, T. Arai, T. Yoshitomi, T. Araki, K. Koizumi

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

The aim of this study was to characterize lung lesions by means of the uptake, retention and washout of 201 Tl, and to quantify the sensitivity of 201 Tl SPET (single photon emission tomography) in detecting mediastinal and hilar lymph nodes. A total of 68 patients with lung lesions (tumours and inflammation) underwent both helical computed tomography (CT) and 201 Tl SPET examinations. Uptake, retention and washout parameters were calculated from early and delayed 201 Tl SPET by drawing regions of interest over the primary lesion and the background of the lung. The findings on 201 Tl SPET were compared with those on CT and surgical findings. A significant difference in the retention index (RI) was observed between primary malignant and benign lesions. In detecting lymph nodes, the sensitivity, specificity and negative predictive value were 83%, 60% and 90% respectively for early 201 Tl SPET, and 50%, 80% and 80% respectively for delayed 201 Tl SPET. 201 Tl SPET with semi-quantitative analysis, especially RI, helps to differentiate between malignant and benign lung lesions. Lymph nodes larger than 1 cm on CT but not showing 201 Tl uptake could be considered non-metastatic lesions.

Original languageEnglish (US)
Pages (from-to)411-416
Number of pages6
JournalNuclear Medicine Communications
Volume19
Issue number5
DOIs
StatePublished - Jan 1 1998
Externally publishedYes

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Photons
Lymph Nodes
Tomography
Lung
Spiral Computed Tomography
Inflammation
Sensitivity and Specificity
Neoplasms

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

Detection of lung lesions and lymph nodes with 201 t1 spet . / Arbab, Ali Syed; Toyama, K.; Arai, T.; Yoshitomi, T.; Araki, T.; Koizumi, K.

In: Nuclear Medicine Communications, Vol. 19, No. 5, 01.01.1998, p. 411-416.

Research output: Contribution to journalArticle

Arbab, AS, Toyama, K, Arai, T, Yoshitomi, T, Araki, T & Koizumi, K 1998, ' Detection of lung lesions and lymph nodes with 201 t1 spet ', Nuclear Medicine Communications, vol. 19, no. 5, pp. 411-416. https://doi.org/10.1080/00006231-199805000-00002
Arbab, Ali Syed ; Toyama, K. ; Arai, T. ; Yoshitomi, T. ; Araki, T. ; Koizumi, K. / Detection of lung lesions and lymph nodes with 201 t1 spet In: Nuclear Medicine Communications. 1998 ; Vol. 19, No. 5. pp. 411-416.
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