Determination of optical probe interrogation field of near-infrared reflectance: Phantom and Monte Carlo study

Ali N. Bahadur, Cole A. Giller, Dheerendra Kashyap, Hanli Liu

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

An optical probe used to localize human brain tissues in vivo has been reported previously. It was able to sense the underlying tissue structure with an optical interrogation field, termed as "look ahead distance" (LAD). A new side-firing probe has been designed with its optical window along its side. We have defined the optical interrogation field of the new side probe as "look aside distance" (LASD). The purpose of this study is to understand the dependence of the LAD and LASD on the optical properties of tissue, the light source intensity, and the integration time of the detector, using experimental and computational methods. The results show that a decrease in light intensity does decrease the LAD and LASD and that an increase in integration time of detection may not necessarily improve the depths of LAD and LASD. Furthermore, Monte Carlo simulation results suggest that the LAD/LASD decreases with an increase in reduced scattering coefficient to a point, after which the LAD/LASD remains constant. We expect that an optical interrogation field of a tip or side probe is approximately 1-2 mm in white matter and 2-3.5 mm in gray matter. These conclusions will help us optimally manipulate the parameter settings during surgery and determine the spatial resolution of the probe.

Original languageEnglish (US)
Pages (from-to)5552-5561
Number of pages10
JournalApplied Optics
Volume46
Issue number23
DOIs
StatePublished - Aug 10 2007
Externally publishedYes

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interrogation
Infrared radiation
reflectance
probes
Tissue
Computational methods
Surgery
Light sources
Brain
Optical properties
Scattering
Detectors
scattering coefficients
surgery
luminous intensity
brain
light sources
spatial resolution

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics

Cite this

Determination of optical probe interrogation field of near-infrared reflectance : Phantom and Monte Carlo study. / Bahadur, Ali N.; Giller, Cole A.; Kashyap, Dheerendra; Liu, Hanli.

In: Applied Optics, Vol. 46, No. 23, 10.08.2007, p. 5552-5561.

Research output: Contribution to journalArticle

Bahadur, Ali N. ; Giller, Cole A. ; Kashyap, Dheerendra ; Liu, Hanli. / Determination of optical probe interrogation field of near-infrared reflectance : Phantom and Monte Carlo study. In: Applied Optics. 2007 ; Vol. 46, No. 23. pp. 5552-5561.
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